Explore RUBCN gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
| Target ID |
GM-IP13880
|
| Target Name |
RUBCN
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9711
|
| Gene ID |
100070138 (Equus caballus), 100502698 (Mus musculus), 100856511 (Canis lupus familiaris), 101098570 (Felis catus)
303885 (Rattus norvegicus), 508354 (Bos taurus), 9711 (Homo sapiens)
|
| Target Alternative Names |
1700021K19Rik,5330403K09,Beclin-1 associated RUN domain containing protein (Baron),KIAA0226,RGD1305422,RUBCN,RUBICON,Rubcn,Rubicon,Run domain Beclin-1-interacting and cysteine-rich domain-containing protein,SCAR15,mKIAA0226
|
| Uniprot Accession |
Q80U62,Q92622
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000010420, ENSMUSG00000035629, ENSCAFG00845029259, ENSBTAG00000001890, ENSG00000145016
|
RUBCN siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9711 | Pre-made Human RUBCN/SCAR15/RUBICON siRNA oligo Duplex | 9711 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo303885 | Pre-made Rat Rubcn/RGD1305422 siRNA oligo Duplex | 303885 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100502698 | Pre-made Mouse Rubcn/Rubicon/mKIAA0226 siRNA oligo Duplex | 100502698 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098570 | Pre-made Cat/Feline RUBCN siRNA oligo Duplex | 101098570 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100856511 | Pre-made Dog/Canine RUBCN siRNA oligo Duplex | 100856511 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508354 | Pre-made Bovines/Cattle RUBCN/KIAA0226 siRNA oligo Duplex | 508354 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070138 | Pre-made Equine/Horse RUBCN/KIAA0226 siRNA oligo Duplex | 100070138 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RUBCN antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP13880-Ab | Human | Anti-Human RUBCN monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP13880-Ab | Rat | Anti-Rat RUBCN monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP13880-Ab | Mouse | Anti-Mouse RUBCN monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP13880-Ab | Cat/Feline | Anti-Cat/Feline RUBCN monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP13880-Ab | Dog/Canine | Anti-Dog/Canine RUBCN monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP13880-Ab | Bovines/Cattle | Anti-Bovines/Cattle RUBCN monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP13880-Ab | Equine/Horse | Anti-Equine/Horse RUBCN monoclonal antibody | mab | | Detail |
RUBCN recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP13880-Ag | Human | Human RUBCN recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP13880-Ag | Rat | Rat RUBCN recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP13880-Ag | Mouse | Mouse RUBCN recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP13880-Ag | Cat/Feline | Cat/Feline RUBCN recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP13880-Ag | Dog/Canine | Dog/Canine RUBCN recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP13880-Ag | Bovines/Cattle | Bovines/Cattle RUBCN recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP13880-Ag | Equine/Horse | Equine/Horse RUBCN recombinant protein | Mammalian cell | Detail |
