Recombinant multi-species DEPDC5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DEPDC5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
The Alternative Names of target: DEE111,DEP domain-containing protein 5,DEP.5,DEPDC5,Depdc5,FFEVF,FFEVF1,FPEVF,GATOR1 complex protein DEPDC5

Target products collectionGo to DEPDC5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13865-Ag-1/ GM-Tg-hg-IP13865-Ag-2 Human DEPDC5 protein Human
GM-Tg-rg-IP13865-Ag-1/ GM-Tg-rg-IP13865-Ag-2 Rat DEPDC5 protein Rat
GM-Tg-mg-IP13865-Ag-1/ GM-Tg-mg-IP13865-Ag-2 Mouse DEPDC5 protein Mouse
GM-Tg-cynog-IP13865-Ag-1/ GM-Tg-cynog-IP13865-Ag-2 Cynomolgus/Rhesus macaque DEPDC5 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13865-Ag-1/ GM-Tg-felg-IP13865-Ag-2 Feline DEPDC5 protein Feline
GM-Tg-cang-IP13865-Ag-1/ GM-Tg-cang-IP13865-Ag-2 Canine DEPDC5 protein Canine
GM-Tg-bovg-IP13865-Ag-1/ GM-Tg-bovg-IP13865-Ag-2 Bovine DEPDC5 protein Bovine
GM-Tg-equg-IP13865-Ag-1/ GM-Tg-equg-IP13865-Ag-2 Equine DEPDC5 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13865-Ag-1/ GM-Tg-hg-IP13865-Ag-2; GM-Tg-rg-IP13865-Ag-1/ GM-Tg-rg-IP13865-Ag-2;
GM-Tg-mg-IP13865-Ag-1/ GM-Tg-mg-IP13865-Ag-2; GM-Tg-cynog-IP13865-Ag-1/ GM-Tg-cynog-IP13865-Ag-2;
GM-Tg-felg-IP13865-Ag-1/ GM-Tg-felg-IP13865-Ag-2; GM-Tg-cang-IP13865-Ag-1/ GM-Tg-cang-IP13865-Ag-2;
GM-Tg-bovg-IP13865-Ag-1/ GM-Tg-bovg-IP13865-Ag-2; GM-Tg-equg-IP13865-Ag-1/ GM-Tg-equg-IP13865-Ag-2
Products Name DEPDC5 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DEPDC5
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DEPDC5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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