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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
| Target ID |
GM-IP13865
|
| Target Name |
DEPDC5
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
9681
|
| Gene ID |
100058243 (Equus caballus), 101099661 (Felis catus), 277854 (Mus musculus), 305464 (Rattus norvegicus) 477546 (Canis lupus familiaris), 521542 (Bos taurus), 718522 (Macaca mulatta), 9681 (Homo sapiens)
|
| Target Alternative Names |
DEE111,DEP domain-containing protein 5,DEP.5,DEPDC5,Depdc5,FFEVF,FFEVF1,FPEVF,GATOR1 complex protein DEPDC5
|
| Uniprot Accession |
P61460,O75140
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000014746, ENSMUSG00000037426, ENSCAFG00845025431, ENSBTAG00000001295, ENSMMUG00000021727, ENSG00000100150
|
DEPDC5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9681 | Pre-made Human DEPDC5/DEP.5/FFEVF siRNA oligo Duplex | 9681 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo305464 | Pre-made Rat Depdc5 siRNA oligo Duplex | 305464 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo277854 | Pre-made Mouse Depdc5 siRNA oligo Duplex | 277854 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718522 | Pre-made Cynomolgus/Rhesus macaque DEPDC5 siRNA oligo Duplex | 718522 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099661 | Pre-made Cat/Feline DEPDC5 siRNA oligo Duplex | 101099661 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477546 | Pre-made Dog/Canine DEPDC5 siRNA oligo Duplex | 477546 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo521542 | Pre-made Bovines/Cattle DEPDC5 siRNA oligo Duplex | 521542 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058243 | Pre-made Equine/Horse DEPDC5 siRNA oligo Duplex | 100058243 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DEPDC5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP13865-Ab | Human | Anti-Human DEPDC5 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP13865-Ab | Rat | Anti-Rat DEPDC5 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP13865-Ab | Mouse | Anti-Mouse DEPDC5 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP13865-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DEPDC5 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP13865-Ab | Cat/Feline | Anti-Cat/Feline DEPDC5 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP13865-Ab | Dog/Canine | Anti-Dog/Canine DEPDC5 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP13865-Ab | Bovines/Cattle | Anti-Bovines/Cattle DEPDC5 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP13865-Ab | Equine/Horse | Anti-Equine/Horse DEPDC5 monoclonal antibody | mab | | Detail |
DEPDC5 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP13865-Ag | Human | Human DEPDC5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP13865-Ag | Rat | Rat DEPDC5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP13865-Ag | Mouse | Mouse DEPDC5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP13865-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DEPDC5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP13865-Ag | Cat/Feline | Cat/Feline DEPDC5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP13865-Ag | Dog/Canine | Dog/Canine DEPDC5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP13865-Ag | Bovines/Cattle | Bovines/Cattle DEPDC5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP13865-Ag | Equine/Horse | Equine/Horse DEPDC5 recombinant protein | Mammalian cell | Detail |