Recombinant multi-species NCOR2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NCOR2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]
The Alternative Names of target: CTG repeat protein 26,CTG26,N-CoR,N-CoR2,NCOR2,Ncor2,Nuclear receptor corepressor 2,SMAP270,SMRT,SMRTE,SMRTE-tau,SMRTe,Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT),T3 receptor-associating factor (TRAC),TNRC14,TRAC,TRAC-1,TRAC1,Thyroid-,retinoic-acid-receptor-associated corepressor

Target products collectionGo to NCOR2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13826-Ag-1/ GM-Tg-hg-IP13826-Ag-2 Human NCOR2 protein Human
GM-Tg-rg-IP13826-Ag-1/ GM-Tg-rg-IP13826-Ag-2 Rat NCOR2 protein Rat
GM-Tg-mg-IP13826-Ag-1/ GM-Tg-mg-IP13826-Ag-2 Mouse NCOR2 protein Mouse
GM-Tg-cynog-IP13826-Ag-1/ GM-Tg-cynog-IP13826-Ag-2 Cynomolgus/Rhesus macaque NCOR2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13826-Ag-1/ GM-Tg-felg-IP13826-Ag-2 Feline NCOR2 protein Feline
GM-Tg-cang-IP13826-Ag-1/ GM-Tg-cang-IP13826-Ag-2 Canine NCOR2 protein Canine
GM-Tg-bovg-IP13826-Ag-1/ GM-Tg-bovg-IP13826-Ag-2 Bovine NCOR2 protein Bovine
GM-Tg-equg-IP13826-Ag-1/ GM-Tg-equg-IP13826-Ag-2 Equine NCOR2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13826-Ag-1/ GM-Tg-hg-IP13826-Ag-2; GM-Tg-rg-IP13826-Ag-1/ GM-Tg-rg-IP13826-Ag-2;
GM-Tg-mg-IP13826-Ag-1/ GM-Tg-mg-IP13826-Ag-2; GM-Tg-cynog-IP13826-Ag-1/ GM-Tg-cynog-IP13826-Ag-2;
GM-Tg-felg-IP13826-Ag-1/ GM-Tg-felg-IP13826-Ag-2; GM-Tg-cang-IP13826-Ag-1/ GM-Tg-cang-IP13826-Ag-2;
GM-Tg-bovg-IP13826-Ag-1/ GM-Tg-bovg-IP13826-Ag-2; GM-Tg-equg-IP13826-Ag-1/ GM-Tg-equg-IP13826-Ag-2
Products Name NCOR2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NCOR2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NCOR2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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