Explore NCOR2 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]
| Target ID |
GM-IP13826
|
| Target Name |
NCOR2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
9612
|
| Gene ID |
100146720 (Equus caballus), 101083973 (Felis catus), 20602 (Mus musculus), 360801 (Rattus norvegicus) 486242 (Canis lupus familiaris), 538549 (Bos taurus), 706261 (Macaca mulatta), 9612 (Homo sapiens)
|
| Target Alternative Names |
CTG repeat protein 26,CTG26,N-CoR,N-CoR2,NCOR2,Ncor2,Nuclear receptor corepressor 2,SMAP270,SMRT,SMRTE,SMRTE-tau,SMRTe,Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT),T3 receptor-associating factor (TRAC),TNRC14,TRAC,TRAC-1,TRAC1,Thyroid-,retinoic-acid-receptor-associated corepressor
|
| Uniprot Accession |
Q9WU42,Q9Y618
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000007272, ENSMUSG00000029478, ENSCAFG00845016132, ENSBTAG00000024603, ENSMMUG00000023107, ENSG00000196498
|
NCOR2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9612 | Pre-made Human NCOR2/SMRT/TRAC siRNA oligo Duplex | 9612 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360801 | Pre-made Rat Ncor2 siRNA oligo Duplex | 360801 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20602 | Pre-made Mouse Ncor2/SMRT/N-CoR siRNA oligo Duplex | 20602 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706261 | Pre-made Cynomolgus/Rhesus macaque NCOR2 siRNA oligo Duplex | 706261 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083973 | Pre-made Cat/Feline NCOR2 siRNA oligo Duplex | 101083973 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486242 | Pre-made Dog/Canine NCOR2 siRNA oligo Duplex | 486242 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo538549 | Pre-made Bovines/Cattle NCOR2 siRNA oligo Duplex | 538549 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146720 | Pre-made Equine/Horse NCOR2 siRNA oligo Duplex | 100146720 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NCOR2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP13826-Ab | Human | Anti-Human NCOR2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP13826-Ab | Rat | Anti-Rat NCOR2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP13826-Ab | Mouse | Anti-Mouse NCOR2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP13826-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NCOR2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP13826-Ab | Cat/Feline | Anti-Cat/Feline NCOR2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP13826-Ab | Dog/Canine | Anti-Dog/Canine NCOR2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP13826-Ab | Bovines/Cattle | Anti-Bovines/Cattle NCOR2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP13826-Ab | Equine/Horse | Anti-Equine/Horse NCOR2 monoclonal antibody | mab | | Detail |
NCOR2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP13826-Ag | Human | Human NCOR2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP13826-Ag | Rat | Rat NCOR2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP13826-Ag | Mouse | Mouse NCOR2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP13826-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NCOR2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP13826-Ag | Cat/Feline | Cat/Feline NCOR2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP13826-Ag | Dog/Canine | Dog/Canine NCOR2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP13826-Ag | Bovines/Cattle | Bovines/Cattle NCOR2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP13826-Ag | Equine/Horse | Equine/Horse NCOR2 recombinant protein | Mammalian cell | Detail |