Recombinant multi-species BAG2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BAG2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2610042A13Rik,BAG family molecular chaperone regulator 2,BAG-2,BAG2,Bag2,Bcl-2-associated athanogene 2,dJ417I1.2

Target products collectionGo to BAG2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13794-Ag-1/ GM-Tg-hg-IP13794-Ag-2 Human BAG2 protein Human
GM-Tg-rg-IP13794-Ag-1/ GM-Tg-rg-IP13794-Ag-2 Rat BAG2 protein Rat
GM-Tg-mg-IP13794-Ag-1/ GM-Tg-mg-IP13794-Ag-2 Mouse BAG2 protein Mouse
GM-Tg-cynog-IP13794-Ag-1/ GM-Tg-cynog-IP13794-Ag-2 Cynomolgus/Rhesus macaque BAG2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13794-Ag-1/ GM-Tg-felg-IP13794-Ag-2 Feline BAG2 protein Feline
GM-Tg-cang-IP13794-Ag-1/ GM-Tg-cang-IP13794-Ag-2 Canine BAG2 protein Canine
GM-Tg-bovg-IP13794-Ag-1/ GM-Tg-bovg-IP13794-Ag-2 Bovine BAG2 protein Bovine
GM-Tg-equg-IP13794-Ag-1/ GM-Tg-equg-IP13794-Ag-2 Equine BAG2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13794-Ag-1/ GM-Tg-hg-IP13794-Ag-2; GM-Tg-rg-IP13794-Ag-1/ GM-Tg-rg-IP13794-Ag-2;
GM-Tg-mg-IP13794-Ag-1/ GM-Tg-mg-IP13794-Ag-2; GM-Tg-cynog-IP13794-Ag-1/ GM-Tg-cynog-IP13794-Ag-2;
GM-Tg-felg-IP13794-Ag-1/ GM-Tg-felg-IP13794-Ag-2; GM-Tg-cang-IP13794-Ag-1/ GM-Tg-cang-IP13794-Ag-2;
GM-Tg-bovg-IP13794-Ag-1/ GM-Tg-bovg-IP13794-Ag-2; GM-Tg-equg-IP13794-Ag-1/ GM-Tg-equg-IP13794-Ag-2
Products Name BAG2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name BAG2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BAG2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.