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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP13794
|
| Target Name |
BAG2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9532
|
| Gene ID |
100070045 (Equus caballus), 101100209 (Felis catus), 213539 (Mus musculus), 506107 (Bos taurus)
610506 (Canis lupus familiaris), 690038 (Rattus norvegicus), 712778 (Macaca mulatta), 9532 (Homo sapiens)
|
| Target Alternative Names |
2610042A13Rik,BAG family molecular chaperone regulator 2,BAG-2,BAG2,Bag2,Bcl-2-associated athanogene 2,dJ417I1.2
|
| Uniprot Accession |
Q91YN9,Q3ZBG5,O95816
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSMUSG00000042215, ENSCAFG00845013818, ENSG00000112208
|
BAG2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9532 | Pre-made Human BAG2/BAG-2/dJ417I1.2 siRNA oligo Duplex | 9532 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo690038 | Pre-made Rat Bag2 siRNA oligo Duplex | 690038 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo213539 | Pre-made Mouse Bag2/2610042A13Rik siRNA oligo Duplex | 213539 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712778 | Pre-made Cynomolgus/Rhesus macaque BAG2 siRNA oligo Duplex | 712778 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100209 | Pre-made Cat/Feline BAG2 siRNA oligo Duplex | 101100209 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo610506 | Pre-made Dog/Canine BAG2 siRNA oligo Duplex | 610506 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506107 | Pre-made Bovines/Cattle BAG2 siRNA oligo Duplex | 506107 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070045 | Pre-made Equine/Horse BAG2 siRNA oligo Duplex | 100070045 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BAG2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP13794-Ab | Human | Anti-Human BAG2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP13794-Ab | Rat | Anti-Rat BAG2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP13794-Ab | Mouse | Anti-Mouse BAG2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP13794-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BAG2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP13794-Ab | Cat/Feline | Anti-Cat/Feline BAG2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP13794-Ab | Dog/Canine | Anti-Dog/Canine BAG2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP13794-Ab | Bovines/Cattle | Anti-Bovines/Cattle BAG2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP13794-Ab | Equine/Horse | Anti-Equine/Horse BAG2 monoclonal antibody | mab | | Detail |
BAG2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP13794-Ag | Human | Human BAG2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP13794-Ag | Rat | Rat BAG2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP13794-Ag | Mouse | Mouse BAG2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP13794-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BAG2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP13794-Ag | Cat/Feline | Cat/Feline BAG2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP13794-Ag | Dog/Canine | Dog/Canine BAG2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP13794-Ag | Bovines/Cattle | Bovines/Cattle BAG2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP13794-Ag | Equine/Horse | Equine/Horse BAG2 recombinant protein | Mammalian cell | Detail |
