Recombinant multi-species TIFA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TIFA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an adapter protein involved in adaptive and innate immunity. This protein includes a forkhead-associated (FHA) domain that specifically binds to phosphorylated serine and threonine residues. In response to bacterial infection, the encoded host cell protein undergoes an intermolecular interaction between the FHA domain and a phosphorylated threonine that leads to protein oligomerization and stimulation of the NF-kappa B and other downstream signaling pathways. This protein exhibits reduced expression in hepatocellular carcinoma and may suppress hepatocellular carcinoma progression. This protein may also play a role in the DNA damage response. [provided by RefSeq, Jun 2018]
The Alternative Names of target: Ab2-389,Putative MAPK-activating protein PM14,Putative NF-kappa-B-activating protein 20,T2BP,T2bp,T6BP,TIFA,TIFAA,TRAF-interacting protein with FHA domain-containing protein A,TRAF2-binding protein,Tifa

Target products collectionGo to TIFA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13633-Ag-1/ GM-Tg-hg-IP13633-Ag-2 Human TIFA protein Human
GM-Tg-rg-IP13633-Ag-1/ GM-Tg-rg-IP13633-Ag-2 Rat TIFA protein Rat
GM-Tg-mg-IP13633-Ag-1/ GM-Tg-mg-IP13633-Ag-2 Mouse TIFA protein Mouse
GM-Tg-cynog-IP13633-Ag-1/ GM-Tg-cynog-IP13633-Ag-2 Cynomolgus/Rhesus macaque TIFA protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13633-Ag-1/ GM-Tg-felg-IP13633-Ag-2 Feline TIFA protein Feline
GM-Tg-cang-IP13633-Ag-1/ GM-Tg-cang-IP13633-Ag-2 Canine TIFA protein Canine
GM-Tg-bovg-IP13633-Ag-1/ GM-Tg-bovg-IP13633-Ag-2 Bovine TIFA protein Bovine
GM-Tg-equg-IP13633-Ag-1/ GM-Tg-equg-IP13633-Ag-2 Equine TIFA protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13633-Ag-1/ GM-Tg-hg-IP13633-Ag-2; GM-Tg-rg-IP13633-Ag-1/ GM-Tg-rg-IP13633-Ag-2;
GM-Tg-mg-IP13633-Ag-1/ GM-Tg-mg-IP13633-Ag-2; GM-Tg-cynog-IP13633-Ag-1/ GM-Tg-cynog-IP13633-Ag-2;
GM-Tg-felg-IP13633-Ag-1/ GM-Tg-felg-IP13633-Ag-2; GM-Tg-cang-IP13633-Ag-1/ GM-Tg-cang-IP13633-Ag-2;
GM-Tg-bovg-IP13633-Ag-1/ GM-Tg-bovg-IP13633-Ag-2; GM-Tg-equg-IP13633-Ag-1/ GM-Tg-equg-IP13633-Ag-2
Products Name TIFA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TIFA
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TIFA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.