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Target
sublocation: Introcelluar Protein.
This gene encodes an adapter protein involved in adaptive and innate immunity. This protein includes a forkhead-associated (FHA) domain that specifically binds to phosphorylated serine and threonine residues. In response to bacterial infection, the encoded host cell protein undergoes an intermolecular interaction between the FHA domain and a phosphorylated threonine that leads to protein oligomerization and stimulation of the NF-kappa B and other downstream signaling pathways. This protein exhibits reduced expression in hepatocellular carcinoma and may suppress hepatocellular carcinoma progression. This protein may also play a role in the DNA damage response. [provided by RefSeq, Jun 2018]
| Target ID |
GM-IP13633
|
| Target Name |
TIFA
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
92610
|
| Gene ID |
100064257 (Equus caballus), 101080453 (Felis catus), 211550 (Mus musculus), 310877 (Rattus norvegicus) 487905 (Canis lupus familiaris), 700865 (Macaca mulatta), 783855 (Bos taurus), 92610 (Homo sapiens)
|
| Target Alternative Names |
Ab2-389,Putative MAPK-activating protein PM14,Putative NF-kappa-B-activating protein 20,T2BP,T2bp,T6BP,TIFA,TIFAA,TRAF-interacting protein with FHA domain-containing protein A,TRAF2-binding protein,Tifa
|
| Uniprot Accession |
Q793I8,Q5XIB9,A2VDM0,Q96CG3
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000004523, ENSMUSG00000046688, ENSCAFG00845016552, ENSMMUG00000015589, ENSBTAG00000049422, ENSG00000145365
|
Pre-made viral vector of TIFA cDNA Clones/ORF Plasmid
TIFA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo92610 | Pre-made Human TIFA/T2BP/T6BP siRNA oligo Duplex | 92610 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo310877 | Pre-made Rat Tifa/T2bp/Ab2-389 siRNA oligo Duplex | 310877 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo211550 | Pre-made Mouse Tifa/T2bp siRNA oligo Duplex | 211550 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700865 | Pre-made Cynomolgus/Rhesus macaque TIFA siRNA oligo Duplex | 700865 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080453 | Pre-made Cat/Feline TIFA siRNA oligo Duplex | 101080453 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487905 | Pre-made Dog/Canine TIFA siRNA oligo Duplex | 487905 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo783855 | Pre-made Bovines/Cattle TIFA siRNA oligo Duplex | 783855 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064257 | Pre-made Equine/Horse TIFA siRNA oligo Duplex | 100064257 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TIFA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP13633-Ab | Human | Anti-Human TIFA monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP13633-Ab | Rat | Anti-Rat TIFA monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP13633-Ab | Mouse | Anti-Mouse TIFA monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP13633-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TIFA monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP13633-Ab | Cat/Feline | Anti-Cat/Feline TIFA monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP13633-Ab | Dog/Canine | Anti-Dog/Canine TIFA monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP13633-Ab | Bovines/Cattle | Anti-Bovines/Cattle TIFA monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP13633-Ab | Equine/Horse | Anti-Equine/Horse TIFA monoclonal antibody | mab | | Detail |
TIFA recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP13633-Ag | Human | Human TIFA recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP13633-Ag | Rat | Rat TIFA recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP13633-Ag | Mouse | Mouse TIFA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP13633-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TIFA recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP13633-Ag | Cat/Feline | Cat/Feline TIFA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP13633-Ag | Dog/Canine | Dog/Canine TIFA recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP13633-Ag | Bovines/Cattle | Bovines/Cattle TIFA recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP13633-Ag | Equine/Horse | Equine/Horse TIFA recombinant protein | Mammalian cell | Detail |