Recombinant multi-species PCBP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PCBP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. This gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2018]
The Alternative Names of target: Alpha-CP2,HNRNPE2,HNRPE2,Heterogeneous nuclear ribonucleoprotein E2 (hnRNP E2),Hnrpx,PCBP2,Pcbp2,Poly(rC)-binding protein 2,alphaCP-2,hnRNP-E2

Target products collectionGo to PCBP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1328-Ag-1/ GM-Tg-hg-IP1328-Ag-2 Human PCBP2 protein Human
GM-Tg-rg-IP1328-Ag-1/ GM-Tg-rg-IP1328-Ag-2 Rat PCBP2 protein Rat
GM-Tg-mg-IP1328-Ag-1/ GM-Tg-mg-IP1328-Ag-2 Mouse PCBP2 protein Mouse
GM-Tg-cynog-IP1328-Ag-1/ GM-Tg-cynog-IP1328-Ag-2 Cynomolgus/Rhesus macaque PCBP2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1328-Ag-1/ GM-Tg-felg-IP1328-Ag-2 Feline PCBP2 protein Feline
GM-Tg-cang-IP1328-Ag-1/ GM-Tg-cang-IP1328-Ag-2 Canine PCBP2 protein Canine
GM-Tg-bovg-IP1328-Ag-1/ GM-Tg-bovg-IP1328-Ag-2 Bovine PCBP2 protein Bovine
GM-Tg-equg-IP1328-Ag-1/ GM-Tg-equg-IP1328-Ag-2 Equine PCBP2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1328-Ag-1/ GM-Tg-hg-IP1328-Ag-2; GM-Tg-rg-IP1328-Ag-1/ GM-Tg-rg-IP1328-Ag-2;
GM-Tg-mg-IP1328-Ag-1/ GM-Tg-mg-IP1328-Ag-2; GM-Tg-cynog-IP1328-Ag-1/ GM-Tg-cynog-IP1328-Ag-2;
GM-Tg-felg-IP1328-Ag-1/ GM-Tg-felg-IP1328-Ag-2; GM-Tg-cang-IP1328-Ag-1/ GM-Tg-cang-IP1328-Ag-2;
GM-Tg-bovg-IP1328-Ag-1/ GM-Tg-bovg-IP1328-Ag-2; GM-Tg-equg-IP1328-Ag-1/ GM-Tg-equg-IP1328-Ag-2
Products Name PCBP2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PCBP2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PCBP2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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