Recombinant multi-species HSD17B6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HSD17B6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. [provided by RefSeq, Aug 2013]
The Alternative Names of target: 17-beta-HSD 6,17-beta-HSD6,17-beta-hydroxysteroid dehydrogenase type 6,17betaHSD9,3-alpha->beta-hydroxysteroid epimerase (3-alpha->beta-HSE),HSD17B6,HSE,Hsd17b6,Hsd17b9,Oxidative 3-alpha hydroxysteroid dehydrogenase,RODH,Rdh8,SDR9C6,Short chain dehydrogenase/reductase family 9C member 6

Target products collectionGo to HSD17B6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13223-Ag-1/ GM-Tg-hg-IP13223-Ag-2 Human HSD17B6 protein Human
GM-Tg-rg-IP13223-Ag-1/ GM-Tg-rg-IP13223-Ag-2 Rat HSD17B6 protein Rat
GM-Tg-mg-IP13223-Ag-1/ GM-Tg-mg-IP13223-Ag-2 Mouse HSD17B6 protein Mouse
GM-Tg-cynog-IP13223-Ag-1/ GM-Tg-cynog-IP13223-Ag-2 Cynomolgus/Rhesus macaque HSD17B6 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13223-Ag-1/ GM-Tg-felg-IP13223-Ag-2 Feline HSD17B6 protein Feline
GM-Tg-cang-IP13223-Ag-1/ GM-Tg-cang-IP13223-Ag-2 Canine HSD17B6 protein Canine
GM-Tg-bovg-IP13223-Ag-1/ GM-Tg-bovg-IP13223-Ag-2 Bovine HSD17B6 protein Bovine
GM-Tg-equg-IP13223-Ag-1/ GM-Tg-equg-IP13223-Ag-2 Equine HSD17B6 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13223-Ag-1/ GM-Tg-hg-IP13223-Ag-2; GM-Tg-rg-IP13223-Ag-1/ GM-Tg-rg-IP13223-Ag-2;
GM-Tg-mg-IP13223-Ag-1/ GM-Tg-mg-IP13223-Ag-2; GM-Tg-cynog-IP13223-Ag-1/ GM-Tg-cynog-IP13223-Ag-2;
GM-Tg-felg-IP13223-Ag-1/ GM-Tg-felg-IP13223-Ag-2; GM-Tg-cang-IP13223-Ag-1/ GM-Tg-cang-IP13223-Ag-2;
GM-Tg-bovg-IP13223-Ag-1/ GM-Tg-bovg-IP13223-Ag-2; GM-Tg-equg-IP13223-Ag-1/ GM-Tg-equg-IP13223-Ag-2
Products Name HSD17B6 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HSD17B6
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HSD17B6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.