Explore HSD17B6 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. [provided by RefSeq, Aug 2013]
| Target ID |
GM-IP13223
|
| Target Name |
HSD17B6
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
8630
|
| Gene ID |
101088341 (Felis catus), 27400 (Mus musculus), 481118 (Canis lupus familiaris), 713549 (Macaca mulatta) 8630 (Homo sapiens)
|
| Target Alternative Names |
17-beta-HSD 6,17-beta-HSD6,17-beta-hydroxysteroid dehydrogenase type 6,17betaHSD9,3-alpha->beta-hydroxysteroid epimerase (3-alpha->beta-HSE),HSD17B6,HSE,Hsd17b6,Hsd17b9,Oxidative 3-alpha hydroxysteroid dehydrogenase,RODH,Rdh8,SDR9C6,Short chain dehydrogenase/reductase family 9C member 6
|
| Uniprot Accession |
Q9R092,O14756
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSMUSG00000025396, ENSCAFG00845009238, ENSMMUG00000057617, ENSG00000025423
|
HSD17B6 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8630 | Pre-made Human HSD17B6/HSE/RODH siRNA oligo Duplex | 8630 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo27400 | Pre-made Mouse Hsd17b6/Rdh8/Hsd17b9 siRNA oligo Duplex | 27400 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713549 | Pre-made Cynomolgus/Rhesus macaque HSD17B6 siRNA oligo Duplex | 713549 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088341 | Pre-made Cat/Feline HSD17B6 siRNA oligo Duplex | 101088341 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481118 | Pre-made Dog/Canine HSD17B6 siRNA oligo Duplex | 481118 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
HSD17B6 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP13223-Ab | Human | Anti-Human HSD17B6 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP13223-Ab | Mouse | Anti-Mouse HSD17B6 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP13223-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HSD17B6 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP13223-Ab | Cat/Feline | Anti-Cat/Feline HSD17B6 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP13223-Ab | Dog/Canine | Anti-Dog/Canine HSD17B6 monoclonal antibody | mab | | Detail |
HSD17B6 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP13223-Ag | Human | Human HSD17B6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP13223-Ag | Mouse | Mouse HSD17B6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP13223-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HSD17B6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP13223-Ag | Cat/Feline | Cat/Feline HSD17B6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP13223-Ag | Dog/Canine | Dog/Canine HSD17B6 recombinant protein | Mammalian cell | Detail |