Recombinant multi-species CBFA2T3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CBFA2T3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
The Alternative Names of target: A630044F12Rik,CBFA2T3,Cbfa2t3,Cbfa2t3h,ETO-2,ETO2,Eto2,MTG16,MTG8-related protein 2,MTGR2,Myeloid translocation gene on chromosome 16 protein (hMTG16),Protein CBFA2T3,RUNX1T3,ZMYND4,Zinc finger MYND domain-containing protein 4

Target products collectionGo to CBFA2T3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13222-Ag-1/ GM-Tg-hg-IP13222-Ag-2 Human CBFA2T3 protein Human
GM-Tg-rg-IP13222-Ag-1/ GM-Tg-rg-IP13222-Ag-2 Rat CBFA2T3 protein Rat
GM-Tg-mg-IP13222-Ag-1/ GM-Tg-mg-IP13222-Ag-2 Mouse CBFA2T3 protein Mouse
GM-Tg-cynog-IP13222-Ag-1/ GM-Tg-cynog-IP13222-Ag-2 Cynomolgus/Rhesus macaque CBFA2T3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13222-Ag-1/ GM-Tg-felg-IP13222-Ag-2 Feline CBFA2T3 protein Feline
GM-Tg-cang-IP13222-Ag-1/ GM-Tg-cang-IP13222-Ag-2 Canine CBFA2T3 protein Canine
GM-Tg-bovg-IP13222-Ag-1/ GM-Tg-bovg-IP13222-Ag-2 Bovine CBFA2T3 protein Bovine
GM-Tg-equg-IP13222-Ag-1/ GM-Tg-equg-IP13222-Ag-2 Equine CBFA2T3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13222-Ag-1/ GM-Tg-hg-IP13222-Ag-2; GM-Tg-rg-IP13222-Ag-1/ GM-Tg-rg-IP13222-Ag-2;
GM-Tg-mg-IP13222-Ag-1/ GM-Tg-mg-IP13222-Ag-2; GM-Tg-cynog-IP13222-Ag-1/ GM-Tg-cynog-IP13222-Ag-2;
GM-Tg-felg-IP13222-Ag-1/ GM-Tg-felg-IP13222-Ag-2; GM-Tg-cang-IP13222-Ag-1/ GM-Tg-cang-IP13222-Ag-2;
GM-Tg-bovg-IP13222-Ag-1/ GM-Tg-bovg-IP13222-Ag-2; GM-Tg-equg-IP13222-Ag-1/ GM-Tg-equg-IP13222-Ag-2
Products Name CBFA2T3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CBFA2T3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CBFA2T3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.