Explore CBFA2T3 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
| Target ID |
GM-IP13222
|
| Target Name |
CBFA2T3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
863
|
| Gene ID |
100051426 (Equus caballus), 101099675 (Felis catus), 12398 (Mus musculus), 361431 (Rattus norvegicus)
489660 (Canis lupus familiaris), 523815 (Bos taurus), 698233 (Macaca mulatta), 863 (Homo sapiens)
|
| Target Alternative Names |
A630044F12Rik,CBFA2T3,Cbfa2t3,Cbfa2t3h,ETO-2,ETO2,Eto2,MTG16,MTG8-related protein 2,MTGR2,Myeloid translocation gene on chromosome 16 protein (hMTG16),Protein CBFA2T3,RUNX1T3,ZMYND4,Zinc finger MYND domain-containing protein 4
|
| Uniprot Accession |
O54972,O75081
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000003668, ENSMUSG00000006362, ENSCAFG00845002914, ENSBTAG00000010927, ENSMMUG00000063909, ENSG00000129993
|
CBFA2T3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo863 | Pre-made Human CBFA2T3/ETO2/MTG16 siRNA oligo Duplex | 863 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo361431 | Pre-made Rat Cbfa2t3 siRNA oligo Duplex | 361431 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12398 | Pre-made Mouse Cbfa2t3/Eto2/ETO-2 siRNA oligo Duplex | 12398 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698233 | Pre-made Cynomolgus/Rhesus macaque CBFA2T3 siRNA oligo Duplex | 698233 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099675 | Pre-made Cat/Feline CBFA2T3 siRNA oligo Duplex | 101099675 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489660 | Pre-made Dog/Canine CBFA2T3 siRNA oligo Duplex | 489660 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo523815 | Pre-made Bovines/Cattle CBFA2T3 siRNA oligo Duplex | 523815 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051426 | Pre-made Equine/Horse CBFA2T3 siRNA oligo Duplex | 100051426 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CBFA2T3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP13222-Ab | Human | Anti-Human CBFA2T3 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP13222-Ab | Rat | Anti-Rat CBFA2T3 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP13222-Ab | Mouse | Anti-Mouse CBFA2T3 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP13222-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CBFA2T3 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP13222-Ab | Cat/Feline | Anti-Cat/Feline CBFA2T3 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP13222-Ab | Dog/Canine | Anti-Dog/Canine CBFA2T3 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP13222-Ab | Bovines/Cattle | Anti-Bovines/Cattle CBFA2T3 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP13222-Ab | Equine/Horse | Anti-Equine/Horse CBFA2T3 monoclonal antibody | mab | | Detail |
CBFA2T3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP13222-Ag | Human | Human CBFA2T3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP13222-Ag | Rat | Rat CBFA2T3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP13222-Ag | Mouse | Mouse CBFA2T3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP13222-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CBFA2T3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP13222-Ag | Cat/Feline | Cat/Feline CBFA2T3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP13222-Ag | Dog/Canine | Dog/Canine CBFA2T3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP13222-Ag | Bovines/Cattle | Bovines/Cattle CBFA2T3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP13222-Ag | Equine/Horse | Equine/Horse CBFA2T3 recombinant protein | Mammalian cell | Detail |
