Recombinant multi-species TP63/p63 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TP63/p63 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. [provided by RefSeq, Aug 2016]
The Alternative Names of target: AIS,B(p51A),B(p51B),Chronic ulcerative stomatitis protein (CUSP),EEC3,KET,Keratinocyte transcription factor KET,Ket,LMS,NBP,OFC8,P51/P63,P63,P73l,RHS,SHFM4,TP53CP,TP53L,TP63,TP73L,Tp63,Tp73l,Transformation-related protein 63 (TP63),Trp53rp1,Trp63,Tumor protein 63,Tumor protein p73-like (p73L),p40,p51,p53CP,p63,p73H,p73L

Target products collectionGo to TP63/p63 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13220-Ag-1/ GM-Tg-hg-IP13220-Ag-2 Human TP63/p63 protein Human
GM-Tg-rg-IP13220-Ag-1/ GM-Tg-rg-IP13220-Ag-2 Rat TP63/p63 protein Rat
GM-Tg-mg-IP13220-Ag-1/ GM-Tg-mg-IP13220-Ag-2 Mouse TP63/p63 protein Mouse
GM-Tg-cynog-IP13220-Ag-1/ GM-Tg-cynog-IP13220-Ag-2 Cynomolgus/Rhesus macaque TP63/p63 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13220-Ag-1/ GM-Tg-felg-IP13220-Ag-2 Feline TP63/p63 protein Feline
GM-Tg-cang-IP13220-Ag-1/ GM-Tg-cang-IP13220-Ag-2 Canine TP63/p63 protein Canine
GM-Tg-bovg-IP13220-Ag-1/ GM-Tg-bovg-IP13220-Ag-2 Bovine TP63/p63 protein Bovine
GM-Tg-equg-IP13220-Ag-1/ GM-Tg-equg-IP13220-Ag-2 Equine TP63/p63 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13220-Ag-1/ GM-Tg-hg-IP13220-Ag-2; GM-Tg-rg-IP13220-Ag-1/ GM-Tg-rg-IP13220-Ag-2;
GM-Tg-mg-IP13220-Ag-1/ GM-Tg-mg-IP13220-Ag-2; GM-Tg-cynog-IP13220-Ag-1/ GM-Tg-cynog-IP13220-Ag-2;
GM-Tg-felg-IP13220-Ag-1/ GM-Tg-felg-IP13220-Ag-2; GM-Tg-cang-IP13220-Ag-1/ GM-Tg-cang-IP13220-Ag-2;
GM-Tg-bovg-IP13220-Ag-1/ GM-Tg-bovg-IP13220-Ag-2; GM-Tg-equg-IP13220-Ag-1/ GM-Tg-equg-IP13220-Ag-2
Products Name TP63/p63 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TP63/p63
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TP63/p63 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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