Recombinant multi-species Spartan/SPRTN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Spartan/SPRTN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]
The Alternative Names of target: C1orf124,C28H1orf124,C4H1orf124,DNA damage protein targeting VCP (DVC1),DNA-dependent metalloprotease SPRTN,DVC1,Gm505,PRO4323,Protein with SprT-like domain at the N terminus (Spartan),RGD1559496,SPRTN,Spartan,Sprtn,spartan

Target products collectionGo to Spartan/SPRTN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP12771-Ag-1/ GM-Tg-hg-IP12771-Ag-2 Human Spartan/SPRTN protein Human
GM-Tg-rg-IP12771-Ag-1/ GM-Tg-rg-IP12771-Ag-2 Rat Spartan/SPRTN protein Rat
GM-Tg-mg-IP12771-Ag-1/ GM-Tg-mg-IP12771-Ag-2 Mouse Spartan/SPRTN protein Mouse
GM-Tg-cynog-IP12771-Ag-1/ GM-Tg-cynog-IP12771-Ag-2 Cynomolgus/Rhesus macaque Spartan/SPRTN protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP12771-Ag-1/ GM-Tg-felg-IP12771-Ag-2 Feline Spartan/SPRTN protein Feline
GM-Tg-cang-IP12771-Ag-1/ GM-Tg-cang-IP12771-Ag-2 Canine Spartan/SPRTN protein Canine
GM-Tg-bovg-IP12771-Ag-1/ GM-Tg-bovg-IP12771-Ag-2 Bovine Spartan/SPRTN protein Bovine
GM-Tg-equg-IP12771-Ag-1/ GM-Tg-equg-IP12771-Ag-2 Equine Spartan/SPRTN protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP12771-Ag-1/ GM-Tg-hg-IP12771-Ag-2; GM-Tg-rg-IP12771-Ag-1/ GM-Tg-rg-IP12771-Ag-2;
GM-Tg-mg-IP12771-Ag-1/ GM-Tg-mg-IP12771-Ag-2; GM-Tg-cynog-IP12771-Ag-1/ GM-Tg-cynog-IP12771-Ag-2;
GM-Tg-felg-IP12771-Ag-1/ GM-Tg-felg-IP12771-Ag-2; GM-Tg-cang-IP12771-Ag-1/ GM-Tg-cang-IP12771-Ag-2;
GM-Tg-bovg-IP12771-Ag-1/ GM-Tg-bovg-IP12771-Ag-2; GM-Tg-equg-IP12771-Ag-1/ GM-Tg-equg-IP12771-Ag-2
Products Name Spartan/SPRTN protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Spartan/SPRTN
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Spartan/SPRTN protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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