Explore Spartan/SPRTN gene products and cross-species
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biological information, expression tools, and therapeutic
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]
| Target ID |
GM-IP12771
|
| Target Name |
Spartan/SPRTN
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
83932
|
| Gene ID |
100060623 (Equus caballus), 101090214 (Felis catus), 244666 (Mus musculus), 292101 (Rattus norvegicus)
488972 (Canis lupus familiaris), 534918 (Bos taurus), 713543 (Macaca mulatta), 83932 (Homo sapiens)
|
| Target Alternative Names |
C1orf124,C28H1orf124,C4H1orf124,DNA damage protein targeting VCP (DVC1),DNA-dependent metalloprotease SPRTN,DVC1,Gm505,PRO4323,Protein with SprT-like domain at the N terminus (Spartan),RGD1559496,SPRTN,Spartan,Sprtn,spartan
|
| Uniprot Accession |
G3X912,D3ZVU1,A5D979,Q9H040
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000023916, ENSMUSG00000031986, ENSCAFG00845000572, ENSBTAG00000006112, ENSMMUG00000005244, ENSG00000010072
|
Spartan/SPRTN siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo83932 | Pre-made Human SPRTN/DVC1/PRO4323 siRNA oligo Duplex | 83932 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo292101 | Pre-made Rat Sprtn/RGD1559496 siRNA oligo Duplex | 292101 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo244666 | Pre-made Mouse Sprtn/Gm505 siRNA oligo Duplex | 244666 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713543 | Pre-made Cynomolgus/Rhesus macaque SPRTN siRNA oligo Duplex | 713543 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090214 | Pre-made Cat/Feline SPRTN siRNA oligo Duplex | 101090214 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488972 | Pre-made Dog/Canine SPRTN/C4H1orf124 siRNA oligo Duplex | 488972 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo534918 | Pre-made Bovines/Cattle SPRTN/C1orf124/C28H1orf124 siRNA oligo Duplex | 534918 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060623 | Pre-made Equine/Horse SPRTN siRNA oligo Duplex | 100060623 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Spartan/SPRTN antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP12771-Ab | Human | Anti-Human Spartan/SPRTN monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP12771-Ab | Rat | Anti-Rat Spartan/SPRTN monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP12771-Ab | Mouse | Anti-Mouse Spartan/SPRTN monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP12771-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Spartan/SPRTN monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP12771-Ab | Cat/Feline | Anti-Cat/Feline Spartan/SPRTN monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP12771-Ab | Dog/Canine | Anti-Dog/Canine Spartan/SPRTN monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP12771-Ab | Bovines/Cattle | Anti-Bovines/Cattle Spartan/SPRTN monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP12771-Ab | Equine/Horse | Anti-Equine/Horse Spartan/SPRTN monoclonal antibody | mab | | Detail |
Spartan/SPRTN recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP12771-Ag | Human | Human Spartan/SPRTN recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP12771-Ag | Rat | Rat Spartan/SPRTN recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP12771-Ag | Mouse | Mouse Spartan/SPRTN recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP12771-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Spartan/SPRTN recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP12771-Ag | Cat/Feline | Cat/Feline Spartan/SPRTN recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP12771-Ag | Dog/Canine | Dog/Canine Spartan/SPRTN recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP12771-Ag | Bovines/Cattle | Bovines/Cattle Spartan/SPRTN recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP12771-Ag | Equine/Horse | Equine/Horse Spartan/SPRTN recombinant protein | Mammalian cell | Detail |
