Recombinant multi-species MAFK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAFK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM, Nov 2008]
The Alternative Names of target: Erythroid transcription factor NF-E2 p18 subunit,MAFK,Mafk,NF-E2,NFE2U,Nfe2u,P18,Transcription factor MafK

Target products collectionGo to MAFK products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP12261-Ag-1/ GM-Tg-hg-IP12261-Ag-2 Human MAFK protein Human
GM-Tg-rg-IP12261-Ag-1/ GM-Tg-rg-IP12261-Ag-2 Rat MAFK protein Rat
GM-Tg-mg-IP12261-Ag-1/ GM-Tg-mg-IP12261-Ag-2 Mouse MAFK protein Mouse
GM-Tg-cynog-IP12261-Ag-1/ GM-Tg-cynog-IP12261-Ag-2 Cynomolgus/Rhesus macaque MAFK protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP12261-Ag-1/ GM-Tg-felg-IP12261-Ag-2 Feline MAFK protein Feline
GM-Tg-cang-IP12261-Ag-1/ GM-Tg-cang-IP12261-Ag-2 Canine MAFK protein Canine
GM-Tg-bovg-IP12261-Ag-1/ GM-Tg-bovg-IP12261-Ag-2 Bovine MAFK protein Bovine
GM-Tg-equg-IP12261-Ag-1/ GM-Tg-equg-IP12261-Ag-2 Equine MAFK protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP12261-Ag-1/ GM-Tg-hg-IP12261-Ag-2; GM-Tg-rg-IP12261-Ag-1/ GM-Tg-rg-IP12261-Ag-2;
GM-Tg-mg-IP12261-Ag-1/ GM-Tg-mg-IP12261-Ag-2; GM-Tg-cynog-IP12261-Ag-1/ GM-Tg-cynog-IP12261-Ag-2;
GM-Tg-felg-IP12261-Ag-1/ GM-Tg-felg-IP12261-Ag-2; GM-Tg-cang-IP12261-Ag-1/ GM-Tg-cang-IP12261-Ag-2;
GM-Tg-bovg-IP12261-Ag-1/ GM-Tg-bovg-IP12261-Ag-2; GM-Tg-equg-IP12261-Ag-1/ GM-Tg-equg-IP12261-Ag-2
Products Name MAFK protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MAFK
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAFK protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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