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Target
sublocation: Introcelluar Protein.
The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM, Nov 2008]
| Target ID |
GM-IP12261
|
| Target Name |
MAFK
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7975
|
| Gene ID |
100856391 (Canis lupus familiaris), 101089820 (Felis catus), 111776168 (Equus caballus), 17135 (Mus musculus) 246760 (Rattus norvegicus), 618914 (Bos taurus), 721769 (Macaca mulatta), 7975 (Homo sapiens)
|
| Target Alternative Names |
Erythroid transcription factor NF-E2 p18 subunit,MAFK,Mafk,NF-E2,NFE2U,Nfe2u,P18,Transcription factor MafK
|
| Uniprot Accession |
Q61827,O60675
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSCAFG00845007588, ENSMUSG00000018143, ENSMMUG00000037597, ENSG00000198517
|
Pre-made viral vector of MAFK cDNA Clones/ORF Plasmid
MAFK siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7975 | Pre-made Human MAFK/P18/NFE2U siRNA oligo Duplex | 7975 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo246760 | Pre-made Rat Mafk siRNA oligo Duplex | 246760 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17135 | Pre-made Mouse Mafk/NF-E2/Nfe2u siRNA oligo Duplex | 17135 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721769 | Pre-made Cynomolgus/Rhesus macaque MAFK siRNA oligo Duplex | 721769 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089820 | Pre-made Cat/Feline MAFK siRNA oligo Duplex | 101089820 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100856391 | Pre-made Dog/Canine MAFK siRNA oligo Duplex | 100856391 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo618914 | Pre-made Bovines/Cattle MAFK siRNA oligo Duplex | 618914 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111776168 | Pre-made Equine/Horse MAFK siRNA oligo Duplex | 111776168 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MAFK antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP12261-Ab | Human | Anti-Human MAFK monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP12261-Ab | Rat | Anti-Rat MAFK monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP12261-Ab | Mouse | Anti-Mouse MAFK monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP12261-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MAFK monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP12261-Ab | Cat/Feline | Anti-Cat/Feline MAFK monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP12261-Ab | Dog/Canine | Anti-Dog/Canine MAFK monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP12261-Ab | Bovines/Cattle | Anti-Bovines/Cattle MAFK monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP12261-Ab | Equine/Horse | Anti-Equine/Horse MAFK monoclonal antibody | mab | | Detail |
MAFK recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP12261-Ag | Human | Human MAFK recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP12261-Ag | Rat | Rat MAFK recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP12261-Ag | Mouse | Mouse MAFK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP12261-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MAFK recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP12261-Ag | Cat/Feline | Cat/Feline MAFK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP12261-Ag | Dog/Canine | Dog/Canine MAFK recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP12261-Ag | Bovines/Cattle | Bovines/Cattle MAFK recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP12261-Ag | Equine/Horse | Equine/Horse MAFK recombinant protein | Mammalian cell | Detail |