Recombinant multi-species MFN2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MFN2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CMT2A,CMT2A2,CMT2A2A,CMT2A2B,CPRP1,D630023P19Rik,Fzo,HMSN6A,HSG,MARF,MFN2,MSL,Mfn2,Mitofusin-2,Transmembrane GTPase MFN2

Target products collectionGo to MFN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1173-Ag-1/ GM-Tg-hg-IP1173-Ag-2 Human MFN2 protein Human
GM-Tg-rg-IP1173-Ag-1/ GM-Tg-rg-IP1173-Ag-2 Rat MFN2 protein Rat
GM-Tg-mg-IP1173-Ag-1/ GM-Tg-mg-IP1173-Ag-2 Mouse MFN2 protein Mouse
GM-Tg-cynog-IP1173-Ag-1/ GM-Tg-cynog-IP1173-Ag-2 Cynomolgus/Rhesus macaque MFN2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1173-Ag-1/ GM-Tg-felg-IP1173-Ag-2 Feline MFN2 protein Feline
GM-Tg-cang-IP1173-Ag-1/ GM-Tg-cang-IP1173-Ag-2 Canine MFN2 protein Canine
GM-Tg-bovg-IP1173-Ag-1/ GM-Tg-bovg-IP1173-Ag-2 Bovine MFN2 protein Bovine
GM-Tg-equg-IP1173-Ag-1/ GM-Tg-equg-IP1173-Ag-2 Equine MFN2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1173-Ag-1/ GM-Tg-hg-IP1173-Ag-2; GM-Tg-rg-IP1173-Ag-1/ GM-Tg-rg-IP1173-Ag-2;
GM-Tg-mg-IP1173-Ag-1/ GM-Tg-mg-IP1173-Ag-2; GM-Tg-cynog-IP1173-Ag-1/ GM-Tg-cynog-IP1173-Ag-2;
GM-Tg-felg-IP1173-Ag-1/ GM-Tg-felg-IP1173-Ag-2; GM-Tg-cang-IP1173-Ag-1/ GM-Tg-cang-IP1173-Ag-2;
GM-Tg-bovg-IP1173-Ag-1/ GM-Tg-bovg-IP1173-Ag-2; GM-Tg-equg-IP1173-Ag-1/ GM-Tg-equg-IP1173-Ag-2
Products Name MFN2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MFN2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MFN2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.