Recombinant multi-species TRAF3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TRAF3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. The protein also plays a role in the regulation of antiviral response. Mutations in this are associated with Encephalopathy, acute, infection-induced, herpes-specific 5. [provided by RefSeq, Jul 2020]
The Alternative Names of target: CAP-1,CAP1,CD40 receptor-associated factor 1 (CRAF1),CD40-binding protein (CD40BP),CD40bp,CRAF1,IIAE5,LAP1,LMP1-associated protein 1 (LAP1),RING-type E3 ubiquitin transferase TRAF3,RNF118,T-BAM,TNF receptor-associated factor 3,TRAF3,TRAFAMN,Traf3,amn

Target products collectionGo to TRAF3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11725-Ag-1/ GM-Tg-hg-IP11725-Ag-2 Human TRAF3 protein Human
GM-Tg-rg-IP11725-Ag-1/ GM-Tg-rg-IP11725-Ag-2 Rat TRAF3 protein Rat
GM-Tg-mg-IP11725-Ag-1/ GM-Tg-mg-IP11725-Ag-2 Mouse TRAF3 protein Mouse
GM-Tg-cynog-IP11725-Ag-1/ GM-Tg-cynog-IP11725-Ag-2 Cynomolgus/Rhesus macaque TRAF3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11725-Ag-1/ GM-Tg-felg-IP11725-Ag-2 Feline TRAF3 protein Feline
GM-Tg-cang-IP11725-Ag-1/ GM-Tg-cang-IP11725-Ag-2 Canine TRAF3 protein Canine
GM-Tg-bovg-IP11725-Ag-1/ GM-Tg-bovg-IP11725-Ag-2 Bovine TRAF3 protein Bovine
GM-Tg-equg-IP11725-Ag-1/ GM-Tg-equg-IP11725-Ag-2 Equine TRAF3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11725-Ag-1/ GM-Tg-hg-IP11725-Ag-2; GM-Tg-rg-IP11725-Ag-1/ GM-Tg-rg-IP11725-Ag-2;
GM-Tg-mg-IP11725-Ag-1/ GM-Tg-mg-IP11725-Ag-2; GM-Tg-cynog-IP11725-Ag-1/ GM-Tg-cynog-IP11725-Ag-2;
GM-Tg-felg-IP11725-Ag-1/ GM-Tg-felg-IP11725-Ag-2; GM-Tg-cang-IP11725-Ag-1/ GM-Tg-cang-IP11725-Ag-2;
GM-Tg-bovg-IP11725-Ag-1/ GM-Tg-bovg-IP11725-Ag-2; GM-Tg-equg-IP11725-Ag-1/ GM-Tg-equg-IP11725-Ag-2
Products Name TRAF3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TRAF3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TRAF3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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