Explore TRAF3 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. The protein also plays a role in the regulation of antiviral response. Mutations in this are associated with Encephalopathy, acute, infection-induced, herpes-specific 5. [provided by RefSeq, Jul 2020]
| Target ID |
GM-IP11725
|
| Target Name |
TRAF3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7187
|
| Gene ID |
100055110 (Equus caballus), 101096739 (Felis catus), 22031 (Mus musculus), 362788 (Rattus norvegicus) 490867 (Canis lupus familiaris), 506182 (Bos taurus), 693961 (Macaca mulatta), 7187 (Homo sapiens)
|
| Target Alternative Names |
CAP-1,CAP1,CD40 receptor-associated factor 1 (CRAF1),CD40-binding protein (CD40BP),CD40bp,CRAF1,IIAE5,LAP1,LMP1-associated protein 1 (LAP1),RING-type E3 ubiquitin transferase TRAF3,RNF118,T-BAM,TNF receptor-associated factor 3,TRAF3,TRAFAMN,Traf3,amn
|
| Uniprot Accession |
Q60803,Q13114
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000037175, ENSMUSG00000021277, ENSCAFG00845016806, ENSBTAG00000069778, ENSMMUG00000011752, ENSG00000131323
|
Pre-made viral vector of TRAF3 cDNA Clones/ORF Plasmid
TRAF3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7187 | Pre-made Human TRAF3/CAP1/LAP1 siRNA oligo Duplex | 7187 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362788 | Pre-made Rat Traf3 siRNA oligo Duplex | 362788 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22031 | Pre-made Mouse Traf3/amn/LAP1 siRNA oligo Duplex | 22031 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693961 | Pre-made Cynomolgus/Rhesus macaque TRAF3 siRNA oligo Duplex | 693961 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096739 | Pre-made Cat/Feline TRAF3 siRNA oligo Duplex | 101096739 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490867 | Pre-made Dog/Canine TRAF3 siRNA oligo Duplex | 490867 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506182 | Pre-made Bovines/Cattle TRAF3 siRNA oligo Duplex | 506182 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055110 | Pre-made Equine/Horse TRAF3 siRNA oligo Duplex | 100055110 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TRAF3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP11725-Ab | Human | Anti-Human TRAF3 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP11725-Ab | Rat | Anti-Rat TRAF3 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP11725-Ab | Mouse | Anti-Mouse TRAF3 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP11725-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TRAF3 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP11725-Ab | Cat/Feline | Anti-Cat/Feline TRAF3 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP11725-Ab | Dog/Canine | Anti-Dog/Canine TRAF3 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP11725-Ab | Bovines/Cattle | Anti-Bovines/Cattle TRAF3 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP11725-Ab | Equine/Horse | Anti-Equine/Horse TRAF3 monoclonal antibody | mab | | Detail |
TRAF3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP11725-Ag | Human | Human TRAF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP11725-Ag | Rat | Rat TRAF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP11725-Ag | Mouse | Mouse TRAF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP11725-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TRAF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP11725-Ag | Cat/Feline | Cat/Feline TRAF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP11725-Ag | Dog/Canine | Dog/Canine TRAF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP11725-Ag | Bovines/Cattle | Bovines/Cattle TRAF3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP11725-Ag | Equine/Horse | Equine/Horse TRAF3 recombinant protein | Mammalian cell | Detail |