Recombinant multi-species TPM4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPM4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
The Alternative Names of target: 2610528G24Rik,BDPLT25,HEL-S-108,TM30p1,TPM4,Tpm4,Tpm4.2,Tpm4.2cy,Tropomyosin alpha-4 chain,Tropomyosin-4

Target products collectionGo to TPM4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11718-Ag-1/ GM-Tg-hg-IP11718-Ag-2 Human TPM4 protein Human
GM-Tg-rg-IP11718-Ag-1/ GM-Tg-rg-IP11718-Ag-2 Rat TPM4 protein Rat
GM-Tg-mg-IP11718-Ag-1/ GM-Tg-mg-IP11718-Ag-2 Mouse TPM4 protein Mouse
GM-Tg-cynog-IP11718-Ag-1/ GM-Tg-cynog-IP11718-Ag-2 Cynomolgus/Rhesus macaque TPM4 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11718-Ag-1/ GM-Tg-felg-IP11718-Ag-2 Feline TPM4 protein Feline
GM-Tg-cang-IP11718-Ag-1/ GM-Tg-cang-IP11718-Ag-2 Canine TPM4 protein Canine
GM-Tg-bovg-IP11718-Ag-1/ GM-Tg-bovg-IP11718-Ag-2 Bovine TPM4 protein Bovine
GM-Tg-equg-IP11718-Ag-1/ GM-Tg-equg-IP11718-Ag-2 Equine TPM4 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11718-Ag-1/ GM-Tg-hg-IP11718-Ag-2; GM-Tg-rg-IP11718-Ag-1/ GM-Tg-rg-IP11718-Ag-2;
GM-Tg-mg-IP11718-Ag-1/ GM-Tg-mg-IP11718-Ag-2; GM-Tg-cynog-IP11718-Ag-1/ GM-Tg-cynog-IP11718-Ag-2;
GM-Tg-felg-IP11718-Ag-1/ GM-Tg-felg-IP11718-Ag-2; GM-Tg-cang-IP11718-Ag-1/ GM-Tg-cang-IP11718-Ag-2;
GM-Tg-bovg-IP11718-Ag-1/ GM-Tg-bovg-IP11718-Ag-2; GM-Tg-equg-IP11718-Ag-1/ GM-Tg-equg-IP11718-Ag-2
Products Name TPM4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TPM4
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPM4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.