Explore TPM4 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
| Target ID |
GM-IP11718
|
| Target Name |
TPM4
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7171
|
| Gene ID |
100147533 (Equus caballus), 101092247 (Felis catus), 24852 (Rattus norvegicus), 326618 (Mus musculus) 535277 (Bos taurus), 609879 (Canis lupus familiaris), 7171 (Homo sapiens), 719428 (Macaca mulatta)
|
| Target Alternative Names |
2610528G24Rik,BDPLT25,HEL-S-108,TM30p1,TPM4,Tpm4,Tpm4.2,Tpm4.2cy,Tropomyosin alpha-4 chain,Tropomyosin-4
|
| Uniprot Accession |
P02561,P09495,Q6IRU2,P67936
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000022254, ENSMUSG00000031799, ENSBTAG00000004553, ENSCAFG00845030471, ENSG00000167460, ENSMMUG00000015783
|
Pre-made viral vector of TPM4 cDNA Clones/ORF Plasmid
TPM4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7171 | Pre-made Human TPM4/BDPLT25/HEL-S-108 siRNA oligo Duplex | 7171 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24852 | Pre-made Rat Tpm4/Tpm4.2/Tpm4.2cy siRNA oligo Duplex | 24852 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo326618 | Pre-made Mouse Tpm4/Tpm4.2/Tpm4.2cy siRNA oligo Duplex | 326618 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo719428 | Pre-made Cynomolgus/Rhesus macaque TPM4 siRNA oligo Duplex | 719428 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092247 | Pre-made Cat/Feline TPM4 siRNA oligo Duplex | 101092247 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609879 | Pre-made Dog/Canine TPM4 siRNA oligo Duplex | 609879 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo535277 | Pre-made Bovines/Cattle TPM4 siRNA oligo Duplex | 535277 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100147533 | Pre-made Equine/Horse TPM4 siRNA oligo Duplex | 100147533 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TPM4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP11718-Ab | Human | Anti-Human TPM4 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP11718-Ab | Rat | Anti-Rat TPM4 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP11718-Ab | Mouse | Anti-Mouse TPM4 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP11718-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TPM4 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP11718-Ab | Cat/Feline | Anti-Cat/Feline TPM4 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP11718-Ab | Dog/Canine | Anti-Dog/Canine TPM4 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP11718-Ab | Bovines/Cattle | Anti-Bovines/Cattle TPM4 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP11718-Ab | Equine/Horse | Anti-Equine/Horse TPM4 monoclonal antibody | mab | | Detail |
TPM4 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP11718-Ag | Human | Human TPM4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP11718-Ag | Rat | Rat TPM4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP11718-Ag | Mouse | Mouse TPM4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP11718-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TPM4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP11718-Ag | Cat/Feline | Cat/Feline TPM4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP11718-Ag | Dog/Canine | Dog/Canine TPM4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP11718-Ag | Bovines/Cattle | Bovines/Cattle TPM4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP11718-Ag | Equine/Horse | Equine/Horse TPM4 recombinant protein | Mammalian cell | Detail |