Recombinant multi-species TPM3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPM3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
The Alternative Names of target: CAPM1,CFTD,CMYO4A,CMYO4B,CMYP4A,CMYP4B,Gamma-tropomyosin,HEL-189,HEL-S-82p,NEM1,OK/SW-cl.5,TM-5,TM3,TM30,TM30nm,TM5,TMnm,TPM3,TPM3nu,TPMsk3,TRK,Tm5NM,Tpm-5,Tpm3,Tpm5,Trop-5,Tropomyosin alpha-3 chain,Tropomyosin-3,Tropomyosin-5 (hTM5),gamma-TM,hTM30nm,hTMnm,hscp30

Target products collectionGo to TPM3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11717-Ag-1/ GM-Tg-hg-IP11717-Ag-2 Human TPM3 protein Human
GM-Tg-rg-IP11717-Ag-1/ GM-Tg-rg-IP11717-Ag-2 Rat TPM3 protein Rat
GM-Tg-mg-IP11717-Ag-1/ GM-Tg-mg-IP11717-Ag-2 Mouse TPM3 protein Mouse
GM-Tg-cynog-IP11717-Ag-1/ GM-Tg-cynog-IP11717-Ag-2 Cynomolgus/Rhesus macaque TPM3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11717-Ag-1/ GM-Tg-felg-IP11717-Ag-2 Feline TPM3 protein Feline
GM-Tg-cang-IP11717-Ag-1/ GM-Tg-cang-IP11717-Ag-2 Canine TPM3 protein Canine
GM-Tg-bovg-IP11717-Ag-1/ GM-Tg-bovg-IP11717-Ag-2 Bovine TPM3 protein Bovine
GM-Tg-equg-IP11717-Ag-1/ GM-Tg-equg-IP11717-Ag-2 Equine TPM3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11717-Ag-1/ GM-Tg-hg-IP11717-Ag-2; GM-Tg-rg-IP11717-Ag-1/ GM-Tg-rg-IP11717-Ag-2;
GM-Tg-mg-IP11717-Ag-1/ GM-Tg-mg-IP11717-Ag-2; GM-Tg-cynog-IP11717-Ag-1/ GM-Tg-cynog-IP11717-Ag-2;
GM-Tg-felg-IP11717-Ag-1/ GM-Tg-felg-IP11717-Ag-2; GM-Tg-cang-IP11717-Ag-1/ GM-Tg-cang-IP11717-Ag-2;
GM-Tg-bovg-IP11717-Ag-1/ GM-Tg-bovg-IP11717-Ag-2; GM-Tg-equg-IP11717-Ag-1/ GM-Tg-equg-IP11717-Ag-2
Products Name TPM3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TPM3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPM3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.