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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
| Target ID |
GM-IP11717
|
| Target Name |
TPM3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7170
|
| Gene ID |
100056751 (Equus caballus), 101099019 (Felis catus), 117557 (Rattus norvegicus), 480137 (Canis lupus familiaris) 497019 (Bos taurus), 59069 (Mus musculus), 716336 (Macaca mulatta), 7170 (Homo sapiens)
|
| Target Alternative Names |
CAPM1,CFTD,CMYO4A,CMYO4B,CMYP4A,CMYP4B,Gamma-tropomyosin,HEL-189,HEL-S-82p,NEM1,OK/SW-cl.5,TM-5,TM3,TM30,TM30nm,TM5,TMnm,TPM3,TPM3nu,TPMsk3,TRK,Tm5NM,Tpm-5,Tpm3,Tpm5,Trop-5,Tropomyosin alpha-3 chain,Tropomyosin-3,Tropomyosin-5 (hTM5),gamma-TM,hTM30nm,hTMnm,hscp30
|
| Uniprot Accession |
Q63610,Q5KR47,P21107,P06753
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000002401, ENSCAFG00845015257, ENSBTAG00000033217, ENSMUSG00000027940, ENSMMUG00000010805, ENSG00000143549
|
Pre-made viral vector of TPM3 cDNA Clones/ORF Plasmid
TPM3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7170 | Pre-made Human TPM3/TM3/TM5 siRNA oligo Duplex | 7170 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo117557 | Pre-made Rat Tpm3/Tpm5/TM30nm siRNA oligo Duplex | 117557 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo59069 | Pre-made Mouse Tpm3/TMnm/Tpm5 siRNA oligo Duplex | 59069 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716336 | Pre-made Cynomolgus/Rhesus macaque TPM3 siRNA oligo Duplex | 716336 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099019 | Pre-made Cat/Feline TPM3 siRNA oligo Duplex | 101099019 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480137 | Pre-made Dog/Canine TPM3 siRNA oligo Duplex | 480137 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo497019 | Pre-made Bovines/Cattle TPM3 siRNA oligo Duplex | 497019 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056751 | Pre-made Equine/Horse TPM3 siRNA oligo Duplex | 100056751 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TPM3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP11717-Ab | Human | Anti-Human TPM3 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP11717-Ab | Rat | Anti-Rat TPM3 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP11717-Ab | Mouse | Anti-Mouse TPM3 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP11717-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TPM3 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP11717-Ab | Cat/Feline | Anti-Cat/Feline TPM3 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP11717-Ab | Dog/Canine | Anti-Dog/Canine TPM3 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP11717-Ab | Bovines/Cattle | Anti-Bovines/Cattle TPM3 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP11717-Ab | Equine/Horse | Anti-Equine/Horse TPM3 monoclonal antibody | mab | | Detail |
TPM3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP11717-Ag | Human | Human TPM3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP11717-Ag | Rat | Rat TPM3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP11717-Ag | Mouse | Mouse TPM3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP11717-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TPM3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP11717-Ag | Cat/Feline | Cat/Feline TPM3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP11717-Ag | Dog/Canine | Dog/Canine TPM3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP11717-Ag | Bovines/Cattle | Bovines/Cattle TPM3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP11717-Ag | Equine/Horse | Equine/Horse TPM3 recombinant protein | Mammalian cell | Detail |