Recombinant multi-species MBTPS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MBTPS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009]
The Alternative Names of target: 9630032G22Rik,BRESEK,Endopeptidase S2P,IFAP,KFSD,KFSDX,LRRGT00063,MBTPS2,Mbtps2,Membrane-bound transcription factor site-2 protease,OI19,OLMSX,S2P,Sterol regulatory element-binding proteins intramembrane protease (SREBPs intramembrane protease)

Target products collectionGo to MBTPS2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1157-Ag-1/ GM-Tg-hg-IP1157-Ag-2 Human MBTPS2 protein Human
GM-Tg-rg-IP1157-Ag-1/ GM-Tg-rg-IP1157-Ag-2 Rat MBTPS2 protein Rat
GM-Tg-mg-IP1157-Ag-1/ GM-Tg-mg-IP1157-Ag-2 Mouse MBTPS2 protein Mouse
GM-Tg-cynog-IP1157-Ag-1/ GM-Tg-cynog-IP1157-Ag-2 Cynomolgus/Rhesus macaque MBTPS2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1157-Ag-1/ GM-Tg-felg-IP1157-Ag-2 Feline MBTPS2 protein Feline
GM-Tg-cang-IP1157-Ag-1/ GM-Tg-cang-IP1157-Ag-2 Canine MBTPS2 protein Canine
GM-Tg-bovg-IP1157-Ag-1/ GM-Tg-bovg-IP1157-Ag-2 Bovine MBTPS2 protein Bovine
GM-Tg-equg-IP1157-Ag-1/ GM-Tg-equg-IP1157-Ag-2 Equine MBTPS2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1157-Ag-1/ GM-Tg-hg-IP1157-Ag-2; GM-Tg-rg-IP1157-Ag-1/ GM-Tg-rg-IP1157-Ag-2;
GM-Tg-mg-IP1157-Ag-1/ GM-Tg-mg-IP1157-Ag-2; GM-Tg-cynog-IP1157-Ag-1/ GM-Tg-cynog-IP1157-Ag-2;
GM-Tg-felg-IP1157-Ag-1/ GM-Tg-felg-IP1157-Ag-2; GM-Tg-cang-IP1157-Ag-1/ GM-Tg-cang-IP1157-Ag-2;
GM-Tg-bovg-IP1157-Ag-1/ GM-Tg-bovg-IP1157-Ag-2; GM-Tg-equg-IP1157-Ag-1/ GM-Tg-equg-IP1157-Ag-2
Products Name MBTPS2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MBTPS2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MBTPS2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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