Explore MBTPS2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009]
| Target ID |
GM-IP1157
|
| Target Name |
MBTPS2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
51360
|
| Gene ID |
100051796 (Equus caballus), 101084262 (Felis catus), 119868395 (Canis lupus familiaris), 270669 (Mus musculus) 302705 (Rattus norvegicus), 51360 (Homo sapiens), 696540 (Macaca mulatta)
|
| Target Alternative Names |
9630032G22Rik,BRESEK,Endopeptidase S2P,IFAP,KFSD,KFSDX,LRRGT00063,MBTPS2,Mbtps2,Membrane-bound transcription factor site-2 protease,OI19,OLMSX,S2P,Sterol regulatory element-binding proteins intramembrane protease (SREBPs intramembrane protease)
|
| Uniprot Accession |
Q8CHX6,O43462
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease from KEGG |
Protein processing in endoplasmic reticulum
|
| Gene Ensembl |
ENSECAG00000000437, ENSCAFG00845029854, ENSMUSG00000046873, ENSG00000012174, ENSMMUG00000022467
|
Pre-made viral vector of MBTPS2 cDNA Clones/ORF Plasmid
MBTPS2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo51360 | Pre-made Human MBTPS2/S2P/IFAP siRNA oligo Duplex | 51360 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo302705 | Pre-made Rat Mbtps2/LRRGT00063 siRNA oligo Duplex | 302705 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo270669 | Pre-made Mouse Mbtps2/9630032G22Rik siRNA oligo Duplex | 270669 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696540 | Pre-made Cynomolgus/Rhesus macaque MBTPS2 siRNA oligo Duplex | 696540 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084262 | Pre-made Cat/Feline MBTPS2 siRNA oligo Duplex | 101084262 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo119868395 | Pre-made Dog/Canine MBTPS2 siRNA oligo Duplex | 119868395 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051796 | Pre-made Equine/Horse MBTPS2 siRNA oligo Duplex | 100051796 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MBTPS2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP1157-Ab | Human | Anti-Human MBTPS2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP1157-Ab | Rat | Anti-Rat MBTPS2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP1157-Ab | Mouse | Anti-Mouse MBTPS2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP1157-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MBTPS2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP1157-Ab | Cat/Feline | Anti-Cat/Feline MBTPS2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP1157-Ab | Dog/Canine | Anti-Dog/Canine MBTPS2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP1157-Ab | Equine/Horse | Anti-Equine/Horse MBTPS2 monoclonal antibody | mab | | Detail |
MBTPS2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP1157-Ag | Human | Human MBTPS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP1157-Ag | Rat | Rat MBTPS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP1157-Ag | Mouse | Mouse MBTPS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP1157-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MBTPS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP1157-Ag | Cat/Feline | Cat/Feline MBTPS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP1157-Ag | Dog/Canine | Dog/Canine MBTPS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP1157-Ag | Equine/Horse | Equine/Horse MBTPS2 recombinant protein | Mammalian cell | Detail |