Recombinant multi-species SKP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SKP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 15kDa,2610043E24Rik,2610206H23Rik,Cyclin-A/CDK2-associated protein p19 (p19A),EMC19,OCP-II,OCP2,Organ of Corti protein 2 (OCP-2),Organ of Corti protein II (OCP-II),RNA polymerase II elongation factor-like protein,S-phase kinase-associated protein 1,SIII,SKP1,SKP1A,Skp1,Skp1a,TCEB1L,Tceb1l,Transcription elongation factor B polypeptide 1-like,p19A,p19Skp1,p19skp1

Target products collectionGo to SKP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11394-Ag-1/ GM-Tg-hg-IP11394-Ag-2 Human SKP1 protein Human
GM-Tg-rg-IP11394-Ag-1/ GM-Tg-rg-IP11394-Ag-2 Rat SKP1 protein Rat
GM-Tg-mg-IP11394-Ag-1/ GM-Tg-mg-IP11394-Ag-2 Mouse SKP1 protein Mouse
GM-Tg-cynog-IP11394-Ag-1/ GM-Tg-cynog-IP11394-Ag-2 Cynomolgus/Rhesus macaque SKP1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11394-Ag-1/ GM-Tg-felg-IP11394-Ag-2 Feline SKP1 protein Feline
GM-Tg-cang-IP11394-Ag-1/ GM-Tg-cang-IP11394-Ag-2 Canine SKP1 protein Canine
GM-Tg-bovg-IP11394-Ag-1/ GM-Tg-bovg-IP11394-Ag-2 Bovine SKP1 protein Bovine
GM-Tg-equg-IP11394-Ag-1/ GM-Tg-equg-IP11394-Ag-2 Equine SKP1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11394-Ag-1/ GM-Tg-hg-IP11394-Ag-2; GM-Tg-rg-IP11394-Ag-1/ GM-Tg-rg-IP11394-Ag-2;
GM-Tg-mg-IP11394-Ag-1/ GM-Tg-mg-IP11394-Ag-2; GM-Tg-cynog-IP11394-Ag-1/ GM-Tg-cynog-IP11394-Ag-2;
GM-Tg-felg-IP11394-Ag-1/ GM-Tg-felg-IP11394-Ag-2; GM-Tg-cang-IP11394-Ag-1/ GM-Tg-cang-IP11394-Ag-2;
GM-Tg-bovg-IP11394-Ag-1/ GM-Tg-bovg-IP11394-Ag-2; GM-Tg-equg-IP11394-Ag-1/ GM-Tg-equg-IP11394-Ag-2
Products Name SKP1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SKP1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SKP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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