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Target
sublocation: Introcelluar Protein.
This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP11394
|
| Target Name |
SKP1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6500
|
| Gene ID |
100062946 (Equus caballus), 100423634 (Macaca mulatta), 101099017 (Felis catus), 21402 (Mus musculus) 287280 (Rattus norvegicus), 474682 (Canis lupus familiaris), 615427 (Bos taurus), 6500 (Homo sapiens)
|
| Target Alternative Names |
15kDa,2610043E24Rik,2610206H23Rik,Cyclin-A/CDK2-associated protein p19 (p19A),EMC19,OCP-II,OCP2,Organ of Corti protein 2 (OCP-2),Organ of Corti protein II (OCP-II),RNA polymerase II elongation factor-like protein,S-phase kinase-associated protein 1,SIII,SKP1,SKP1A,Skp1,Skp1a,TCEB1L,Tceb1l,Transcription elongation factor B polypeptide 1-like,p19A,p19Skp1,p19skp1
|
| Uniprot Accession |
Q9WTX5,Q6PEC4,Q3ZCF3,P63208
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000050063, ENSMMUG00000013047, ENSMUSG00000036309, ENSCAFG00845012532, ENSBTAG00000025191, ENSG00000113558
|
Pre-made viral vector of SKP1 cDNA Clones/ORF Plasmid
SKP1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6500 | Pre-made Human SKP1/OCP2/p19A siRNA oligo Duplex | 6500 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo287280 | Pre-made Rat Skp1/Skp1a siRNA oligo Duplex | 287280 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21402 | Pre-made Mouse Skp1/OCP2/p19A siRNA oligo Duplex | 21402 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100423634 | Pre-made Cynomolgus/Rhesus macaque SKP1 siRNA oligo Duplex | 100423634 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099017 | Pre-made Cat/Feline SKP1 siRNA oligo Duplex | 101099017 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474682 | Pre-made Dog/Canine SKP1 siRNA oligo Duplex | 474682 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo615427 | Pre-made Bovines/Cattle SKP1/SKP1A siRNA oligo Duplex | 615427 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062946 | Pre-made Equine/Horse SKP1 siRNA oligo Duplex | 100062946 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SKP1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP11394-Ab | Human | Anti-Human SKP1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP11394-Ab | Rat | Anti-Rat SKP1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP11394-Ab | Mouse | Anti-Mouse SKP1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP11394-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SKP1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP11394-Ab | Cat/Feline | Anti-Cat/Feline SKP1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP11394-Ab | Dog/Canine | Anti-Dog/Canine SKP1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP11394-Ab | Bovines/Cattle | Anti-Bovines/Cattle SKP1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP11394-Ab | Equine/Horse | Anti-Equine/Horse SKP1 monoclonal antibody | mab | | Detail |
SKP1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP11394-Ag | Human | Human SKP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP11394-Ag | Rat | Rat SKP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP11394-Ag | Mouse | Mouse SKP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP11394-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SKP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP11394-Ag | Cat/Feline | Cat/Feline SKP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP11394-Ag | Dog/Canine | Dog/Canine SKP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP11394-Ag | Bovines/Cattle | Bovines/Cattle SKP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP11394-Ag | Equine/Horse | Equine/Horse SKP1 recombinant protein | Mammalian cell | Detail |