Recombinant multi-species SCP2/SCPx protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SCP2/SCPx protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.[provided by RefSeq, Aug 2010]
The Alternative Names of target: Acetyl-CoA C-myristoyltransferase,LOC100297152,NLTP,NSL-TP,NSLIPTR,Non-specific lipid-transfer protein (NSL-TP),Propanoyl-CoA C-acyltransferase,SCOX,SCP-2,SCP-2/3-oxoacyl-CoA thiolase,SCP-2/thiolase,SCP-CHI,SCP-X,SCP-chi,SCP2,SCPX,SCPx,Scp2,Sterol carrier protein 2,Sterol carrier protein X (SCP-X),ns-LTP
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP11043-Ag-1/ GM-Tg-hg-IP11043-Ag-2 | Human SCP2/SCPx protein | Human |
| GM-Tg-rg-IP11043-Ag-1/ GM-Tg-rg-IP11043-Ag-2 | Rat SCP2/SCPx protein | Rat |
| GM-Tg-mg-IP11043-Ag-1/ GM-Tg-mg-IP11043-Ag-2 | Mouse SCP2/SCPx protein | Mouse |
| GM-Tg-cynog-IP11043-Ag-1/ GM-Tg-cynog-IP11043-Ag-2 | Cynomolgus/Rhesus macaque SCP2/SCPx protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP11043-Ag-1/ GM-Tg-felg-IP11043-Ag-2 | Feline SCP2/SCPx protein | Feline |
| GM-Tg-cang-IP11043-Ag-1/ GM-Tg-cang-IP11043-Ag-2 | Canine SCP2/SCPx protein | Canine |
| GM-Tg-bovg-IP11043-Ag-1/ GM-Tg-bovg-IP11043-Ag-2 | Bovine SCP2/SCPx protein | Bovine |
| GM-Tg-equg-IP11043-Ag-1/ GM-Tg-equg-IP11043-Ag-2 | Equine SCP2/SCPx protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP11043-Ag-1/ GM-Tg-hg-IP11043-Ag-2;
GM-Tg-rg-IP11043-Ag-1/ GM-Tg-rg-IP11043-Ag-2;
GM-Tg-mg-IP11043-Ag-1/ GM-Tg-mg-IP11043-Ag-2; GM-Tg-cynog-IP11043-Ag-1/ GM-Tg-cynog-IP11043-Ag-2; GM-Tg-felg-IP11043-Ag-1/ GM-Tg-felg-IP11043-Ag-2; GM-Tg-cang-IP11043-Ag-1/ GM-Tg-cang-IP11043-Ag-2; GM-Tg-bovg-IP11043-Ag-1/ GM-Tg-bovg-IP11043-Ag-2; GM-Tg-equg-IP11043-Ag-1/ GM-Tg-equg-IP11043-Ag-2 |
| Products Name | SCP2/SCPx protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | SCP2/SCPx |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SCP2/SCPx protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
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strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.