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Target
sublocation: Introcelluar Protein.
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.[provided by RefSeq, Aug 2010]
| Target ID |
GM-IP11043
|
| Target Name |
SCP2/SCPx
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6342
|
| Gene ID |
100061338 (Equus caballus), 100297152 (Bos taurus), 101093036 (Felis catus), 20280 (Mus musculus) 25541 (Rattus norvegicus), 479564 (Canis lupus familiaris), 6342 (Homo sapiens), 715765 (Macaca mulatta)
|
| Target Alternative Names |
Acetyl-CoA C-myristoyltransferase,LOC100297152,NLTP,NSL-TP,NSLIPTR,Non-specific lipid-transfer protein (NSL-TP),Propanoyl-CoA C-acyltransferase,SCOX,SCP-2,SCP-2/3-oxoacyl-CoA thiolase,SCP-2/thiolase,SCP-CHI,SCP-X,SCP-chi,SCP2,SCPX,SCPx,Scp2,Sterol carrier protein 2,Sterol carrier protein X (SCP-X),ns-LTP
|
| Uniprot Accession |
P32020,P11915,P22307
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000018459, ENSMUSG00000028603, ENSCAFG00845018123, ENSG00000116171, ENSMMUG00000004952
|
Pre-made viral vector of SCP2/SCPx cDNA Clones/ORF Plasmid
SCP2/SCPx siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6342 | Pre-made Human SCP2/NLTP/SCOX siRNA oligo Duplex | 6342 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25541 | Pre-made Rat Scp2/SCPx/NSLIPTR siRNA oligo Duplex | 25541 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20280 | Pre-made Mouse Scp2/SCPX/SCP-2 siRNA oligo Duplex | 20280 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715765 | Pre-made Cynomolgus/Rhesus macaque SCP2 siRNA oligo Duplex | 715765 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093036 | Pre-made Cat/Feline SCP2 siRNA oligo Duplex | 101093036 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479564 | Pre-made Dog/Canine SCP2 siRNA oligo Duplex | 479564 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100297152 | Pre-made Bovines/Cattle LOC100297152 siRNA oligo Duplex | 100297152 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061338 | Pre-made Equine/Horse SCP2 siRNA oligo Duplex | 100061338 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SCP2/SCPx antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP11043-Ab | Human | Anti-Human SCP2/SCPx monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP11043-Ab | Rat | Anti-Rat SCP2/SCPx monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP11043-Ab | Mouse | Anti-Mouse SCP2/SCPx monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP11043-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SCP2/SCPx monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP11043-Ab | Cat/Feline | Anti-Cat/Feline SCP2/SCPx monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP11043-Ab | Dog/Canine | Anti-Dog/Canine SCP2/SCPx monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP11043-Ab | Bovines/Cattle | Anti-Bovines/Cattle SCP2/SCPx monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP11043-Ab | Equine/Horse | Anti-Equine/Horse SCP2/SCPx monoclonal antibody | mab | | Detail |
SCP2/SCPx recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP11043-Ag | Human | Human SCP2/SCPx recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP11043-Ag | Rat | Rat SCP2/SCPx recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP11043-Ag | Mouse | Mouse SCP2/SCPx recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP11043-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SCP2/SCPx recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP11043-Ag | Cat/Feline | Cat/Feline SCP2/SCPx recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP11043-Ag | Dog/Canine | Dog/Canine SCP2/SCPx recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP11043-Ag | Bovines/Cattle | Bovines/Cattle SCP2/SCPx recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP11043-Ag | Equine/Horse | Equine/Horse SCP2/SCPx recombinant protein | Mammalian cell | Detail |