Recombinant multi-species RFC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RFC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA-dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011]
The Alternative Names of target: 140kDa,A1,Activator 1 140 kDa subunit (A1 140 kDa subunit),Activator 1 large subunit,Activator 1 subunit 1,Alp145,CANVAS,DNA-binding protein PO-GA,MHCBFB,PO-GA,RECC1,RFC,RFC1,RFC140,RFC140),Recc1,Replication factor C 140 kDa subunit (RF-C 140 kDa subunit,Replication factor C large subunit,Replication factor C subunit 1,Rfc1

Target products collectionGo to RFC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10891-Ag-1/ GM-Tg-hg-IP10891-Ag-2 Human RFC1 protein Human
GM-Tg-rg-IP10891-Ag-1/ GM-Tg-rg-IP10891-Ag-2 Rat RFC1 protein Rat
GM-Tg-mg-IP10891-Ag-1/ GM-Tg-mg-IP10891-Ag-2 Mouse RFC1 protein Mouse
GM-Tg-cynog-IP10891-Ag-1/ GM-Tg-cynog-IP10891-Ag-2 Cynomolgus/Rhesus macaque RFC1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10891-Ag-1/ GM-Tg-felg-IP10891-Ag-2 Feline RFC1 protein Feline
GM-Tg-cang-IP10891-Ag-1/ GM-Tg-cang-IP10891-Ag-2 Canine RFC1 protein Canine
GM-Tg-bovg-IP10891-Ag-1/ GM-Tg-bovg-IP10891-Ag-2 Bovine RFC1 protein Bovine
GM-Tg-equg-IP10891-Ag-1/ GM-Tg-equg-IP10891-Ag-2 Equine RFC1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10891-Ag-1/ GM-Tg-hg-IP10891-Ag-2; GM-Tg-rg-IP10891-Ag-1/ GM-Tg-rg-IP10891-Ag-2;
GM-Tg-mg-IP10891-Ag-1/ GM-Tg-mg-IP10891-Ag-2; GM-Tg-cynog-IP10891-Ag-1/ GM-Tg-cynog-IP10891-Ag-2;
GM-Tg-felg-IP10891-Ag-1/ GM-Tg-felg-IP10891-Ag-2; GM-Tg-cang-IP10891-Ag-1/ GM-Tg-cang-IP10891-Ag-2;
GM-Tg-bovg-IP10891-Ag-1/ GM-Tg-bovg-IP10891-Ag-2; GM-Tg-equg-IP10891-Ag-1/ GM-Tg-equg-IP10891-Ag-2
Products Name RFC1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RFC1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RFC1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.