Explore RFC1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA-dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011]
| Target ID |
GM-IP10891
|
| Target Name |
RFC1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5981
|
| Gene ID |
100064382 (Equus caballus), 101094345 (Felis catus), 19687 (Mus musculus), 479112 (Canis lupus familiaris)
514842 (Bos taurus), 5981 (Homo sapiens), 698987 (Macaca mulatta), 89809 (Rattus norvegicus)
|
| Target Alternative Names |
140kDa,A1,Activator 1 140 kDa subunit (A1 140 kDa subunit),Activator 1 large subunit,Activator 1 subunit 1,Alp145,CANVAS,DNA-binding protein PO-GA,MHCBFB,PO-GA,RECC1,RFC,RFC1,RFC140,RFC140),Recc1,Replication factor C 140 kDa subunit (RF-C 140 kDa subunit,Replication factor C large subunit,Replication factor C subunit 1,Rfc1
|
| Uniprot Accession |
P35601,P35251
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer, Breast Cancer
|
| Gene Ensembl |
ENSECAG00000024126, ENSMUSG00000029191, ENSCAFG00845004687, ENSBTAG00000014515, ENSG00000035928, ENSMMUG00000009324
|
RFC1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5981 | Pre-made Human RFC1/A1/RFC siRNA oligo Duplex | 5981 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo89809 | Pre-made Rat Rfc1/Recc1 siRNA oligo Duplex | 89809 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19687 | Pre-made Mouse Rfc1/Recc1/140kDa siRNA oligo Duplex | 19687 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698987 | Pre-made Cynomolgus/Rhesus macaque RFC1 siRNA oligo Duplex | 698987 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094345 | Pre-made Cat/Feline RFC1 siRNA oligo Duplex | 101094345 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479112 | Pre-made Dog/Canine RFC1 siRNA oligo Duplex | 479112 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514842 | Pre-made Bovines/Cattle RFC1 siRNA oligo Duplex | 514842 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064382 | Pre-made Equine/Horse RFC1 siRNA oligo Duplex | 100064382 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RFC1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP10891-Ab | Human | Anti-Human RFC1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP10891-Ab | Rat | Anti-Rat RFC1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP10891-Ab | Mouse | Anti-Mouse RFC1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP10891-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RFC1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP10891-Ab | Cat/Feline | Anti-Cat/Feline RFC1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP10891-Ab | Dog/Canine | Anti-Dog/Canine RFC1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP10891-Ab | Bovines/Cattle | Anti-Bovines/Cattle RFC1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP10891-Ab | Equine/Horse | Anti-Equine/Horse RFC1 monoclonal antibody | mab | | Detail |
RFC1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP10891-Ag | Human | Human RFC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP10891-Ag | Rat | Rat RFC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP10891-Ag | Mouse | Mouse RFC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP10891-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RFC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP10891-Ag | Cat/Feline | Cat/Feline RFC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP10891-Ag | Dog/Canine | Dog/Canine RFC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP10891-Ag | Bovines/Cattle | Bovines/Cattle RFC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP10891-Ag | Equine/Horse | Equine/Horse RFC1 recombinant protein | Mammalian cell | Detail |
