Recombinant multi-species ACTA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ACTA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause a variety of myopathies, including nemaline myopathy, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects with manifestations such as hypotonia. [provided by RefSeq, Sep 2019]
The Alternative Names of target: ACTA,ACTA1,ASMA,Acta-2,Acta1,Actin,Acts,Actsk-1,Alpha-actin-1,CFTD,CFTD1,CFTDM,CMYO2A,CMYO2B,CMYO2C,CMYP2A,CMYP2B,CMYP2C,MPFD,NEM1,NEM2,NEM3,SHPM,alpha skeletal muscle

Target products collectionGo to ACTA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10762-Ag-1/ GM-Tg-hg-IP10762-Ag-2 Human ACTA1 protein Human
GM-Tg-rg-IP10762-Ag-1/ GM-Tg-rg-IP10762-Ag-2 Rat ACTA1 protein Rat
GM-Tg-mg-IP10762-Ag-1/ GM-Tg-mg-IP10762-Ag-2 Mouse ACTA1 protein Mouse
GM-Tg-cynog-IP10762-Ag-1/ GM-Tg-cynog-IP10762-Ag-2 Cynomolgus/Rhesus macaque ACTA1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10762-Ag-1/ GM-Tg-felg-IP10762-Ag-2 Feline ACTA1 protein Feline
GM-Tg-cang-IP10762-Ag-1/ GM-Tg-cang-IP10762-Ag-2 Canine ACTA1 protein Canine
GM-Tg-bovg-IP10762-Ag-1/ GM-Tg-bovg-IP10762-Ag-2 Bovine ACTA1 protein Bovine
GM-Tg-equg-IP10762-Ag-1/ GM-Tg-equg-IP10762-Ag-2 Equine ACTA1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10762-Ag-1/ GM-Tg-hg-IP10762-Ag-2; GM-Tg-rg-IP10762-Ag-1/ GM-Tg-rg-IP10762-Ag-2;
GM-Tg-mg-IP10762-Ag-1/ GM-Tg-mg-IP10762-Ag-2; GM-Tg-cynog-IP10762-Ag-1/ GM-Tg-cynog-IP10762-Ag-2;
GM-Tg-felg-IP10762-Ag-1/ GM-Tg-felg-IP10762-Ag-2; GM-Tg-cang-IP10762-Ag-1/ GM-Tg-cang-IP10762-Ag-2;
GM-Tg-bovg-IP10762-Ag-1/ GM-Tg-bovg-IP10762-Ag-2; GM-Tg-equg-IP10762-Ag-1/ GM-Tg-equg-IP10762-Ag-2
Products Name ACTA1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ACTA1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ACTA1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.