Explore ACTA1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause a variety of myopathies, including nemaline myopathy, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects with manifestations such as hypotonia. [provided by RefSeq, Sep 2019]
| Target ID |
GM-IP10762
|
| Target Name |
ACTA1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
58
|
| Gene ID |
100065454 (Equus caballus), 100426612 (Macaca mulatta), 101095439 (Felis catus), 11459 (Mus musculus) 281592 (Bos taurus), 29437 (Rattus norvegicus), 488984 (Canis lupus familiaris), 58 (Homo sapiens)
|
| Target Alternative Names |
ACTA,ACTA1,ASMA,Acta-2,Acta1,Actin,Acts,Actsk-1,Alpha-actin-1,CFTD,CFTD1,CFTDM,CMYO2A,CMYO2B,CMYO2C,CMYP2A,CMYP2B,CMYP2C,MPFD,NEM1,NEM2,NEM3,SHPM,alpha skeletal muscle
|
| Uniprot Accession |
P68134,P68138,P68136,P68133
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000000207, ENSMMUG00000022086, ENSMUSG00000031972, ENSBTAG00000046332, ENSCAFG00845001416, ENSG00000143632
|
Pre-made viral vector of ACTA1 cDNA Clones/ORF Plasmid
ACTA1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo58 | Pre-made Human ACTA1/ACTA/ASMA siRNA oligo Duplex | 58 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29437 | Pre-made Rat Acta1 siRNA oligo Duplex | 29437 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11459 | Pre-made Mouse Acta1/Acts/Acta-2 siRNA oligo Duplex | 11459 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100426612 | Pre-made Cynomolgus/Rhesus macaque ACTA1 siRNA oligo Duplex | 100426612 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095439 | Pre-made Cat/Feline ACTA1 siRNA oligo Duplex | 101095439 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488984 | Pre-made Dog/Canine ACTA1 siRNA oligo Duplex | 488984 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281592 | Pre-made Bovines/Cattle ACTA1 siRNA oligo Duplex | 281592 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065454 | Pre-made Equine/Horse ACTA1/ACTA siRNA oligo Duplex | 100065454 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ACTA1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP10762-Ab | Human | Anti-Human ACTA1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP10762-Ab | Rat | Anti-Rat ACTA1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP10762-Ab | Mouse | Anti-Mouse ACTA1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP10762-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ACTA1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP10762-Ab | Cat/Feline | Anti-Cat/Feline ACTA1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP10762-Ab | Dog/Canine | Anti-Dog/Canine ACTA1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP10762-Ab | Bovines/Cattle | Anti-Bovines/Cattle ACTA1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP10762-Ab | Equine/Horse | Anti-Equine/Horse ACTA1 monoclonal antibody | mab | | Detail |
ACTA1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP10762-Ag | Human | Human ACTA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP10762-Ag | Rat | Rat ACTA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP10762-Ag | Mouse | Mouse ACTA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP10762-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ACTA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP10762-Ag | Cat/Feline | Cat/Feline ACTA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP10762-Ag | Dog/Canine | Dog/Canine ACTA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP10762-Ag | Bovines/Cattle | Bovines/Cattle ACTA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP10762-Ag | Equine/Horse | Equine/Horse ACTA1 recombinant protein | Mammalian cell | Detail |