Recombinant multi-species CTPS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CTPS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
The Alternative Names of target: A830031M15Rik,CTP synthase 2,CTP synthetase 2,CTPS2,Ctps2,Ctpsh,GATD5B,UTP--ammonia ligase 2
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP10417-Ag-1/ GM-Tg-hg-IP10417-Ag-2 | Human CTPS2 protein | Human |
| GM-Tg-rg-IP10417-Ag-1/ GM-Tg-rg-IP10417-Ag-2 | Rat CTPS2 protein | Rat |
| GM-Tg-mg-IP10417-Ag-1/ GM-Tg-mg-IP10417-Ag-2 | Mouse CTPS2 protein | Mouse |
| GM-Tg-cynog-IP10417-Ag-1/ GM-Tg-cynog-IP10417-Ag-2 | Cynomolgus/Rhesus macaque CTPS2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP10417-Ag-1/ GM-Tg-felg-IP10417-Ag-2 | Feline CTPS2 protein | Feline |
| GM-Tg-cang-IP10417-Ag-1/ GM-Tg-cang-IP10417-Ag-2 | Canine CTPS2 protein | Canine |
| GM-Tg-bovg-IP10417-Ag-1/ GM-Tg-bovg-IP10417-Ag-2 | Bovine CTPS2 protein | Bovine |
| GM-Tg-equg-IP10417-Ag-1/ GM-Tg-equg-IP10417-Ag-2 | Equine CTPS2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP10417-Ag-1/ GM-Tg-hg-IP10417-Ag-2;
GM-Tg-rg-IP10417-Ag-1/ GM-Tg-rg-IP10417-Ag-2;
GM-Tg-mg-IP10417-Ag-1/ GM-Tg-mg-IP10417-Ag-2; GM-Tg-cynog-IP10417-Ag-1/ GM-Tg-cynog-IP10417-Ag-2; GM-Tg-felg-IP10417-Ag-1/ GM-Tg-felg-IP10417-Ag-2; GM-Tg-cang-IP10417-Ag-1/ GM-Tg-cang-IP10417-Ag-2; GM-Tg-bovg-IP10417-Ag-1/ GM-Tg-bovg-IP10417-Ag-2; GM-Tg-equg-IP10417-Ag-1/ GM-Tg-equg-IP10417-Ag-2 |
| Products Name | CTPS2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CTPS2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CTPS2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.