Explore CTPS2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
| Target ID |
GM-IP10417
|
| Target Name |
CTPS2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
56474
|
| Gene ID |
100146439 (Equus caballus), 101097209 (Felis catus), 480851 (Canis lupus familiaris), 55936 (Mus musculus)
56474 (Homo sapiens), 619580 (Rattus norvegicus), 721014 (Macaca mulatta), 767849 (Bos taurus)
|
| Target Alternative Names |
A830031M15Rik,CTP synthase 2,CTP synthetase 2,CTPS2,Ctps2,Ctpsh,GATD5B,UTP--ammonia ligase 2
|
| Uniprot Accession |
P70303,Q9NRF8,Q5U2N0,Q1RMS2
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000017669, ENSCAFG00845030785, ENSMUSG00000031360, ENSG00000047230, ENSMMUG00000004797, ENSBTAG00000017017
|
CTPS2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo56474 | Pre-made Human CTPS2/GATD5B siRNA oligo Duplex | 56474 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo619580 | Pre-made Rat Ctps2 siRNA oligo Duplex | 619580 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo55936 | Pre-made Mouse Ctps2/Ctpsh/A830031M15Rik siRNA oligo Duplex | 55936 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721014 | Pre-made Cynomolgus/Rhesus macaque CTPS2 siRNA oligo Duplex | 721014 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097209 | Pre-made Cat/Feline CTPS2 siRNA oligo Duplex | 101097209 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480851 | Pre-made Dog/Canine CTPS2 siRNA oligo Duplex | 480851 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo767849 | Pre-made Bovines/Cattle CTPS2 siRNA oligo Duplex | 767849 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146439 | Pre-made Equine/Horse CTPS2 siRNA oligo Duplex | 100146439 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CTPS2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP10417-Ab | Human | Anti-Human CTPS2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP10417-Ab | Rat | Anti-Rat CTPS2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP10417-Ab | Mouse | Anti-Mouse CTPS2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP10417-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CTPS2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP10417-Ab | Cat/Feline | Anti-Cat/Feline CTPS2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP10417-Ab | Dog/Canine | Anti-Dog/Canine CTPS2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP10417-Ab | Bovines/Cattle | Anti-Bovines/Cattle CTPS2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP10417-Ab | Equine/Horse | Anti-Equine/Horse CTPS2 monoclonal antibody | mab | | Detail |
CTPS2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP10417-Ag | Human | Human CTPS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP10417-Ag | Rat | Rat CTPS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP10417-Ag | Mouse | Mouse CTPS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP10417-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CTPS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP10417-Ag | Cat/Feline | Cat/Feline CTPS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP10417-Ag | Dog/Canine | Dog/Canine CTPS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP10417-Ag | Bovines/Cattle | Bovines/Cattle CTPS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP10417-Ag | Equine/Horse | Equine/Horse CTPS2 recombinant protein | Mammalian cell | Detail |
