Recombinant multi-species RNF20 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RNF20 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012]
The Alternative Names of target: 4833430L21Rik,BRE1,BRE1-A,BRE1A,E3 ubiquitin-protein ligase BRE1A,RING finger protein 20,RING-type E3 ubiquitin transferase BRE1A,RNF20,Rnf20,hBRE1,mKIAA4116

Target products collectionGo to RNF20 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10398-Ag-1/ GM-Tg-hg-IP10398-Ag-2 Human RNF20 protein Human
GM-Tg-rg-IP10398-Ag-1/ GM-Tg-rg-IP10398-Ag-2 Rat RNF20 protein Rat
GM-Tg-mg-IP10398-Ag-1/ GM-Tg-mg-IP10398-Ag-2 Mouse RNF20 protein Mouse
GM-Tg-cynog-IP10398-Ag-1/ GM-Tg-cynog-IP10398-Ag-2 Cynomolgus/Rhesus macaque RNF20 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10398-Ag-1/ GM-Tg-felg-IP10398-Ag-2 Feline RNF20 protein Feline
GM-Tg-cang-IP10398-Ag-1/ GM-Tg-cang-IP10398-Ag-2 Canine RNF20 protein Canine
GM-Tg-bovg-IP10398-Ag-1/ GM-Tg-bovg-IP10398-Ag-2 Bovine RNF20 protein Bovine
GM-Tg-equg-IP10398-Ag-1/ GM-Tg-equg-IP10398-Ag-2 Equine RNF20 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10398-Ag-1/ GM-Tg-hg-IP10398-Ag-2; GM-Tg-rg-IP10398-Ag-1/ GM-Tg-rg-IP10398-Ag-2;
GM-Tg-mg-IP10398-Ag-1/ GM-Tg-mg-IP10398-Ag-2; GM-Tg-cynog-IP10398-Ag-1/ GM-Tg-cynog-IP10398-Ag-2;
GM-Tg-felg-IP10398-Ag-1/ GM-Tg-felg-IP10398-Ag-2; GM-Tg-cang-IP10398-Ag-1/ GM-Tg-cang-IP10398-Ag-2;
GM-Tg-bovg-IP10398-Ag-1/ GM-Tg-bovg-IP10398-Ag-2; GM-Tg-equg-IP10398-Ag-1/ GM-Tg-equg-IP10398-Ag-2
Products Name RNF20 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RNF20
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RNF20 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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