Explore RNF20 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012]
| Target ID |
GM-IP10398
|
| Target Name |
RNF20
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
56254
|
| Gene ID |
100054384 (Equus caballus), 101097522 (Felis catus), 109331 (Mus musculus), 313216 (Rattus norvegicus)
474788 (Canis lupus familiaris), 513326 (Bos taurus), 56254 (Homo sapiens), 713614 (Macaca mulatta)
|
| Target Alternative Names |
4833430L21Rik,BRE1,BRE1-A,BRE1A,E3 ubiquitin-protein ligase BRE1A,RING finger protein 20,RING-type E3 ubiquitin transferase BRE1A,RNF20,Rnf20,hBRE1,mKIAA4116
|
| Uniprot Accession |
Q5DTM8,A2VDP1,Q5VTR2
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000018149, ENSMUSG00000028309, ENSCAFG00845009367, ENSBTAG00000009516, ENSG00000155827, ENSMMUG00000016670
|
Pre-made viral vector of RNF20 cDNA Clones/ORF Plasmid
RNF20 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo56254 | Pre-made Human RNF20/BRE1/BRE1A siRNA oligo Duplex | 56254 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo313216 | Pre-made Rat Rnf20 siRNA oligo Duplex | 313216 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo109331 | Pre-made Mouse Rnf20/mKIAA4116/4833430L21Rik siRNA oligo Duplex | 109331 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713614 | Pre-made Cynomolgus/Rhesus macaque RNF20 siRNA oligo Duplex | 713614 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097522 | Pre-made Cat/Feline RNF20 siRNA oligo Duplex | 101097522 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474788 | Pre-made Dog/Canine RNF20 siRNA oligo Duplex | 474788 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo513326 | Pre-made Bovines/Cattle RNF20 siRNA oligo Duplex | 513326 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054384 | Pre-made Equine/Horse RNF20 siRNA oligo Duplex | 100054384 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RNF20 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP10398-Ab | Human | Anti-Human RNF20 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP10398-Ab | Rat | Anti-Rat RNF20 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP10398-Ab | Mouse | Anti-Mouse RNF20 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP10398-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RNF20 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP10398-Ab | Cat/Feline | Anti-Cat/Feline RNF20 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP10398-Ab | Dog/Canine | Anti-Dog/Canine RNF20 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP10398-Ab | Bovines/Cattle | Anti-Bovines/Cattle RNF20 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP10398-Ab | Equine/Horse | Anti-Equine/Horse RNF20 monoclonal antibody | mab | | Detail |
RNF20 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP10398-Ag | Human | Human RNF20 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP10398-Ag | Rat | Rat RNF20 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP10398-Ag | Mouse | Mouse RNF20 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP10398-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RNF20 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP10398-Ag | Cat/Feline | Cat/Feline RNF20 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP10398-Ag | Dog/Canine | Dog/Canine RNF20 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP10398-Ag | Bovines/Cattle | Bovines/Cattle RNF20 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP10398-Ag | Equine/Horse | Equine/Horse RNF20 recombinant protein | Mammalian cell | Detail |
