Recombinant multi-species LMOD3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LMOD3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the leiomodin family of proteins. This protein contains three actin-binding domains, a tropomyosin domain, a leucine-rich repeat domain, and a Wiskott-Aldrich syndrome protein homology 2 domain (WH2). Localization of this protein to the pointed ends of thin filaments has been observed, and there is evidence that this protein acts as a catalyst of actin nucleation, and is important to the organization of sarcomeric thin filaments in skeletal muscles. Mutations in this gene have been associated as one cause of Nemaline myopathy, as other genes have also been linked to this disorder. Nemaline myopathy is a disorder characterized by nonprogressive generalized muscle weakness and protein inclusions (nemaline bodies) in skeletal myofibers. Patients with mutations in this gene often present with a severe congenital form of the disorder. [provided by RefSeq, Jan 2015]
The Alternative Names of target: 5430424A14Rik,LMOD3,Leiomodin,Leiomodin-3,Lmod3,NEM10,RGD1564924,fetal form

Target products collectionGo to LMOD3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10392-Ag-1/ GM-Tg-hg-IP10392-Ag-2 Human LMOD3 protein Human
GM-Tg-rg-IP10392-Ag-1/ GM-Tg-rg-IP10392-Ag-2 Rat LMOD3 protein Rat
GM-Tg-mg-IP10392-Ag-1/ GM-Tg-mg-IP10392-Ag-2 Mouse LMOD3 protein Mouse
GM-Tg-cynog-IP10392-Ag-1/ GM-Tg-cynog-IP10392-Ag-2 Cynomolgus/Rhesus macaque LMOD3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10392-Ag-1/ GM-Tg-felg-IP10392-Ag-2 Feline LMOD3 protein Feline
GM-Tg-cang-IP10392-Ag-1/ GM-Tg-cang-IP10392-Ag-2 Canine LMOD3 protein Canine
GM-Tg-bovg-IP10392-Ag-1/ GM-Tg-bovg-IP10392-Ag-2 Bovine LMOD3 protein Bovine
GM-Tg-equg-IP10392-Ag-1/ GM-Tg-equg-IP10392-Ag-2 Equine LMOD3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10392-Ag-1/ GM-Tg-hg-IP10392-Ag-2; GM-Tg-rg-IP10392-Ag-1/ GM-Tg-rg-IP10392-Ag-2;
GM-Tg-mg-IP10392-Ag-1/ GM-Tg-mg-IP10392-Ag-2; GM-Tg-cynog-IP10392-Ag-1/ GM-Tg-cynog-IP10392-Ag-2;
GM-Tg-felg-IP10392-Ag-1/ GM-Tg-felg-IP10392-Ag-2; GM-Tg-cang-IP10392-Ag-1/ GM-Tg-cang-IP10392-Ag-2;
GM-Tg-bovg-IP10392-Ag-1/ GM-Tg-bovg-IP10392-Ag-2; GM-Tg-equg-IP10392-Ag-1/ GM-Tg-equg-IP10392-Ag-2
Products Name LMOD3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name LMOD3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LMOD3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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