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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of the leiomodin family of proteins. This protein contains three actin-binding domains, a tropomyosin domain, a leucine-rich repeat domain, and a Wiskott-Aldrich syndrome protein homology 2 domain (WH2). Localization of this protein to the pointed ends of thin filaments has been observed, and there is evidence that this protein acts as a catalyst of actin nucleation, and is important to the organization of sarcomeric thin filaments in skeletal muscles. Mutations in this gene have been associated as one cause of Nemaline myopathy, as other genes have also been linked to this disorder. Nemaline myopathy is a disorder characterized by nonprogressive generalized muscle weakness and protein inclusions (nemaline bodies) in skeletal myofibers. Patients with mutations in this gene often present with a severe congenital form of the disorder. [provided by RefSeq, Jan 2015]
| Target ID |
GM-IP10392
|
| Target Name |
LMOD3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
56203
|
| Gene ID |
100053299 (Equus caballus), 101090679 (Felis catus), 320502 (Mus musculus), 476558 (Canis lupus familiaris) 500267 (Rattus norvegicus), 509978 (Bos taurus), 56203 (Homo sapiens), 696239 (Macaca mulatta)
|
| Target Alternative Names |
5430424A14Rik,LMOD3,Leiomodin,Leiomodin-3,Lmod3,NEM10,RGD1564924,fetal form
|
| Uniprot Accession |
E9QA62,Q0VAK6
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000008709, ENSMUSG00000044086, ENSCAFG00845010392, ENSBTAG00000021508, ENSG00000163380, ENSMMUG00000008628
|
LMOD3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo56203 | Pre-made Human LMOD3/NEM10 siRNA oligo Duplex | 56203 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo500267 | Pre-made Rat Lmod3/RGD1564924 siRNA oligo Duplex | 500267 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo320502 | Pre-made Mouse Lmod3/5430424A14Rik siRNA oligo Duplex | 320502 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696239 | Pre-made Cynomolgus/Rhesus macaque LMOD3 siRNA oligo Duplex | 696239 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090679 | Pre-made Cat/Feline LMOD3 siRNA oligo Duplex | 101090679 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476558 | Pre-made Dog/Canine LMOD3 siRNA oligo Duplex | 476558 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo509978 | Pre-made Bovines/Cattle LMOD3 siRNA oligo Duplex | 509978 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053299 | Pre-made Equine/Horse LMOD3 siRNA oligo Duplex | 100053299 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LMOD3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP10392-Ab | Human | Anti-Human LMOD3 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP10392-Ab | Rat | Anti-Rat LMOD3 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP10392-Ab | Mouse | Anti-Mouse LMOD3 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP10392-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LMOD3 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP10392-Ab | Cat/Feline | Anti-Cat/Feline LMOD3 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP10392-Ab | Dog/Canine | Anti-Dog/Canine LMOD3 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP10392-Ab | Bovines/Cattle | Anti-Bovines/Cattle LMOD3 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP10392-Ab | Equine/Horse | Anti-Equine/Horse LMOD3 monoclonal antibody | mab | | Detail |
LMOD3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP10392-Ag | Human | Human LMOD3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP10392-Ag | Rat | Rat LMOD3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP10392-Ag | Mouse | Mouse LMOD3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP10392-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LMOD3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP10392-Ag | Cat/Feline | Cat/Feline LMOD3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP10392-Ag | Dog/Canine | Dog/Canine LMOD3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP10392-Ag | Bovines/Cattle | Bovines/Cattle LMOD3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP10392-Ag | Equine/Horse | Equine/Horse LMOD3 recombinant protein | Mammalian cell | Detail |