Recombinant multi-species PRKCB/pan-PKC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRKCB/pan-PKC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
The Alternative Names of target: PKC-B,PKC-Beta,PKC-beta,PKCB,PKCI(2),PKCbeta,PRKCB,PRKCB1,PRKCB2,Pkcb,Prkcb,Prkcb1,Prkcb2,Protein kinase C beta type,pan-PKC

Target products collectionGo to PRKCB/pan-PKC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10303-Ag-1/ GM-Tg-hg-IP10303-Ag-2 Human PRKCB/pan-PKC protein Human
GM-Tg-rg-IP10303-Ag-1/ GM-Tg-rg-IP10303-Ag-2 Rat PRKCB/pan-PKC protein Rat
GM-Tg-mg-IP10303-Ag-1/ GM-Tg-mg-IP10303-Ag-2 Mouse PRKCB/pan-PKC protein Mouse
GM-Tg-cynog-IP10303-Ag-1/ GM-Tg-cynog-IP10303-Ag-2 Cynomolgus/Rhesus macaque PRKCB/pan-PKC protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10303-Ag-1/ GM-Tg-felg-IP10303-Ag-2 Feline PRKCB/pan-PKC protein Feline
GM-Tg-cang-IP10303-Ag-1/ GM-Tg-cang-IP10303-Ag-2 Canine PRKCB/pan-PKC protein Canine
GM-Tg-bovg-IP10303-Ag-1/ GM-Tg-bovg-IP10303-Ag-2 Bovine PRKCB/pan-PKC protein Bovine
GM-Tg-equg-IP10303-Ag-1/ GM-Tg-equg-IP10303-Ag-2 Equine PRKCB/pan-PKC protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10303-Ag-1/ GM-Tg-hg-IP10303-Ag-2; GM-Tg-rg-IP10303-Ag-1/ GM-Tg-rg-IP10303-Ag-2;
GM-Tg-mg-IP10303-Ag-1/ GM-Tg-mg-IP10303-Ag-2; GM-Tg-cynog-IP10303-Ag-1/ GM-Tg-cynog-IP10303-Ag-2;
GM-Tg-felg-IP10303-Ag-1/ GM-Tg-felg-IP10303-Ag-2; GM-Tg-cang-IP10303-Ag-1/ GM-Tg-cang-IP10303-Ag-2;
GM-Tg-bovg-IP10303-Ag-1/ GM-Tg-bovg-IP10303-Ag-2; GM-Tg-equg-IP10303-Ag-1/ GM-Tg-equg-IP10303-Ag-2
Products Name PRKCB/pan-PKC protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PRKCB/pan-PKC
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRKCB/pan-PKC protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.