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Target
sublocation: Introcelluar Protein.
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP10303
|
| Target Name |
PRKCB/pan-PKC
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5579
|
| Gene ID |
100069215 (Equus caballus), 101088970 (Felis catus), 18751 (Mus musculus), 25023 (Rattus norvegicus) 282325 (Bos taurus), 489968 (Canis lupus familiaris), 5579 (Homo sapiens), 701195 (Macaca mulatta)
|
| Target Alternative Names |
PKC-B,PKC-Beta,PKC-beta,PKCB,PKCI(2),PKCbeta,PRKCB,PRKCB1,PRKCB2,Pkcb,Prkcb,Prkcb1,Prkcb2,Protein kinase C beta type,pan-PKC
|
| Uniprot Accession |
P68404,P68403,P05126,P05771
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000017393, ENSMUSG00000052889, ENSBTAG00000020921, ENSCAFG00845001335, ENSG00000166501, ENSMMUG00000014271
|
| Target Classification |
Kinase
|
Pre-made viral vector of PRKCB/pan-PKC cDNA Clones/ORF Plasmid
PRKCB/pan-PKC siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5579 | Pre-made Human PRKCB/PKCB/PRKCB1 siRNA oligo Duplex | 5579 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25023 | Pre-made Rat Prkcb/Pkcb/Prkcb1 siRNA oligo Duplex | 25023 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18751 | Pre-made Mouse Prkcb/Pkcb/PKC-B siRNA oligo Duplex | 18751 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701195 | Pre-made Cynomolgus/Rhesus macaque PRKCB/PRKCB1 siRNA oligo Duplex | 701195 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088970 | Pre-made Cat/Feline PRKCB siRNA oligo Duplex | 101088970 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489968 | Pre-made Dog/Canine PRKCB/PRKCB1 siRNA oligo Duplex | 489968 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282325 | Pre-made Bovines/Cattle PRKCB/PRKCB1 siRNA oligo Duplex | 282325 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069215 | Pre-made Equine/Horse PRKCB siRNA oligo Duplex | 100069215 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PRKCB/pan-PKC antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP10303-Ab | Human | Anti-Human PRKCB/pan-PKC monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP10303-Ab | Rat | Anti-Rat PRKCB/pan-PKC monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP10303-Ab | Mouse | Anti-Mouse PRKCB/pan-PKC monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP10303-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PRKCB/pan-PKC monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP10303-Ab | Cat/Feline | Anti-Cat/Feline PRKCB/pan-PKC monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP10303-Ab | Dog/Canine | Anti-Dog/Canine PRKCB/pan-PKC monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP10303-Ab | Bovines/Cattle | Anti-Bovines/Cattle PRKCB/pan-PKC monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP10303-Ab | Equine/Horse | Anti-Equine/Horse PRKCB/pan-PKC monoclonal antibody | mab | | Detail |
PRKCB/pan-PKC recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP10303-Ag | Human | Human PRKCB/pan-PKC recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP10303-Ag | Rat | Rat PRKCB/pan-PKC recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP10303-Ag | Mouse | Mouse PRKCB/pan-PKC recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP10303-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PRKCB/pan-PKC recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP10303-Ag | Cat/Feline | Cat/Feline PRKCB/pan-PKC recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP10303-Ag | Dog/Canine | Dog/Canine PRKCB/pan-PKC recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP10303-Ag | Bovines/Cattle | Bovines/Cattle PRKCB/pan-PKC recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP10303-Ag | Equine/Horse | Equine/Horse PRKCB/pan-PKC recombinant protein | Mammalian cell | Detail |