Recombinant multi-species OTUB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine OTUB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
The Alternative Names of target: Deubiquitinating enzyme OTUB1,HSPC263,OTB1,OTU domain-containing ubiquitin aldehyde-binding protein 1,OTU1,OTUB1,Otub1,Otubain-1 (hOTU1),Ubiquitin thioesterase OTUB1,Ubiquitin-specific-processing protease OTUB1
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP10198-Ag-1/ GM-Tg-hg-IP10198-Ag-2 | Human OTUB1 protein | Human |
| GM-Tg-rg-IP10198-Ag-1/ GM-Tg-rg-IP10198-Ag-2 | Rat OTUB1 protein | Rat |
| GM-Tg-mg-IP10198-Ag-1/ GM-Tg-mg-IP10198-Ag-2 | Mouse OTUB1 protein | Mouse |
| GM-Tg-cynog-IP10198-Ag-1/ GM-Tg-cynog-IP10198-Ag-2 | Cynomolgus/Rhesus macaque OTUB1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP10198-Ag-1/ GM-Tg-felg-IP10198-Ag-2 | Feline OTUB1 protein | Feline |
| GM-Tg-cang-IP10198-Ag-1/ GM-Tg-cang-IP10198-Ag-2 | Canine OTUB1 protein | Canine |
| GM-Tg-bovg-IP10198-Ag-1/ GM-Tg-bovg-IP10198-Ag-2 | Bovine OTUB1 protein | Bovine |
| GM-Tg-equg-IP10198-Ag-1/ GM-Tg-equg-IP10198-Ag-2 | Equine OTUB1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP10198-Ag-1/ GM-Tg-hg-IP10198-Ag-2;
GM-Tg-rg-IP10198-Ag-1/ GM-Tg-rg-IP10198-Ag-2;
GM-Tg-mg-IP10198-Ag-1/ GM-Tg-mg-IP10198-Ag-2; GM-Tg-cynog-IP10198-Ag-1/ GM-Tg-cynog-IP10198-Ag-2; GM-Tg-felg-IP10198-Ag-1/ GM-Tg-felg-IP10198-Ag-2; GM-Tg-cang-IP10198-Ag-1/ GM-Tg-cang-IP10198-Ag-2; GM-Tg-bovg-IP10198-Ag-1/ GM-Tg-bovg-IP10198-Ag-2; GM-Tg-equg-IP10198-Ag-1/ GM-Tg-equg-IP10198-Ag-2 |
| Products Name | OTUB1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | OTUB1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine OTUB1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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entities. Leveraging the sophisticated
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Through
expression in mammalian cell lines, GMab has
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reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.