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Target
sublocation: Introcelluar Protein.
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP10198
|
| Target Name |
OTUB1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
55611
|
| Gene ID |
100054829 (Equus caballus), 101096843 (Felis catus), 107260 (Mus musculus), 293705 (Rattus norvegicus) 540984 (Bos taurus), 55611 (Homo sapiens), 611228 (Canis lupus familiaris), 717989 (Macaca mulatta)
|
| Target Alternative Names |
Deubiquitinating enzyme OTUB1,HSPC263,OTB1,OTU domain-containing ubiquitin aldehyde-binding protein 1,OTU1,OTUB1,Otub1,Otubain-1 (hOTU1),Ubiquitin thioesterase OTUB1,Ubiquitin-specific-processing protease OTUB1
|
| Uniprot Accession |
Q7TQI3,B2RYG6,Q96FW1
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSMUSG00000024767, ENSBTAG00000003967, ENSG00000167770, ENSCAFG00845030788
|
Pre-made viral vector of OTUB1 cDNA Clones/ORF Plasmid
OTUB1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo55611 | Pre-made Human OTUB1/OTB1/OTU1 siRNA oligo Duplex | 55611 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo293705 | Pre-made Rat Otub1 siRNA oligo Duplex | 293705 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo107260 | Pre-made Mouse Otub1 siRNA oligo Duplex | 107260 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717989 | Pre-made Cynomolgus/Rhesus macaque OTUB1 siRNA oligo Duplex | 717989 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096843 | Pre-made Cat/Feline OTUB1 siRNA oligo Duplex | 101096843 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611228 | Pre-made Dog/Canine OTUB1 siRNA oligo Duplex | 611228 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540984 | Pre-made Bovines/Cattle OTUB1 siRNA oligo Duplex | 540984 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054829 | Pre-made Equine/Horse OTUB1 siRNA oligo Duplex | 100054829 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
OTUB1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP10198-Ab | Human | Anti-Human OTUB1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP10198-Ab | Rat | Anti-Rat OTUB1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP10198-Ab | Mouse | Anti-Mouse OTUB1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP10198-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque OTUB1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP10198-Ab | Cat/Feline | Anti-Cat/Feline OTUB1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP10198-Ab | Dog/Canine | Anti-Dog/Canine OTUB1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP10198-Ab | Bovines/Cattle | Anti-Bovines/Cattle OTUB1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP10198-Ab | Equine/Horse | Anti-Equine/Horse OTUB1 monoclonal antibody | mab | | Detail |
OTUB1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP10198-Ag | Human | Human OTUB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP10198-Ag | Rat | Rat OTUB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP10198-Ag | Mouse | Mouse OTUB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP10198-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque OTUB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP10198-Ag | Cat/Feline | Cat/Feline OTUB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP10198-Ag | Dog/Canine | Dog/Canine OTUB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP10198-Ag | Bovines/Cattle | Bovines/Cattle OTUB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP10198-Ag | Equine/Horse | Equine/Horse OTUB1 recombinant protein | Mammalian cell | Detail |