Recombinant multi-species ABCD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ABCD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ABC39,ABCD2,ALDL1,ALDR,ALDRP,ATP-binding cassette sub-family D member 2,Abcd2,Adrenoleukodystrophy-like 1,Adrenoleukodystrophy-related protein (hALDR),hALDR

Target products collectionGo to ABCD2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0282-Ag-1/ GM-Tg-hg-IP0282-Ag-2 Human ABCD2 protein Human
GM-Tg-rg-IP0282-Ag-1/ GM-Tg-rg-IP0282-Ag-2 Rat ABCD2 protein Rat
GM-Tg-mg-IP0282-Ag-1/ GM-Tg-mg-IP0282-Ag-2 Mouse ABCD2 protein Mouse
GM-Tg-cynog-IP0282-Ag-1/ GM-Tg-cynog-IP0282-Ag-2 Cynomolgus/Rhesus macaque ABCD2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0282-Ag-1/ GM-Tg-felg-IP0282-Ag-2 Feline ABCD2 protein Feline
GM-Tg-cang-IP0282-Ag-1/ GM-Tg-cang-IP0282-Ag-2 Canine ABCD2 protein Canine
GM-Tg-bovg-IP0282-Ag-1/ GM-Tg-bovg-IP0282-Ag-2 Bovine ABCD2 protein Bovine
GM-Tg-equg-IP0282-Ag-1/ GM-Tg-equg-IP0282-Ag-2 Equine ABCD2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0282-Ag-1/ GM-Tg-hg-IP0282-Ag-2; GM-Tg-rg-IP0282-Ag-1/ GM-Tg-rg-IP0282-Ag-2;
GM-Tg-mg-IP0282-Ag-1/ GM-Tg-mg-IP0282-Ag-2; GM-Tg-cynog-IP0282-Ag-1/ GM-Tg-cynog-IP0282-Ag-2;
GM-Tg-felg-IP0282-Ag-1/ GM-Tg-felg-IP0282-Ag-2; GM-Tg-cang-IP0282-Ag-1/ GM-Tg-cang-IP0282-Ag-2;
GM-Tg-bovg-IP0282-Ag-1/ GM-Tg-bovg-IP0282-Ag-2; GM-Tg-equg-IP0282-Ag-1/ GM-Tg-equg-IP0282-Ag-2
Products Name ABCD2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ABCD2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ABCD2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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