Recombinant multi-species NAT2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NAT2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second polymorphic arylamine N-acetyltransferase gene (NAT1), is located near this gene (NAT2). [provided by RefSeq, Sep 2019]
The Alternative Names of target: AAC2,Arylamide acetylase 2,Arylamine N-acetyltransferase 2,N-acetyltransferase type 2 (NAT-2),N-hydroxyarylamine O-acetyltransferase,NAT-2,NAT2,PNAT,Polymorphic arylamine N-acetyltransferase (PNAT)

Target products collectionGo to NAT2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0253-Ag-1/ GM-Tg-hg-IP0253-Ag-2 Human NAT2 protein Human
GM-Tg-rg-IP0253-Ag-1/ GM-Tg-rg-IP0253-Ag-2 Rat NAT2 protein Rat
GM-Tg-mg-IP0253-Ag-1/ GM-Tg-mg-IP0253-Ag-2 Mouse NAT2 protein Mouse
GM-Tg-cynog-IP0253-Ag-1/ GM-Tg-cynog-IP0253-Ag-2 Cynomolgus/Rhesus macaque NAT2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0253-Ag-1/ GM-Tg-felg-IP0253-Ag-2 Feline NAT2 protein Feline
GM-Tg-cang-IP0253-Ag-1/ GM-Tg-cang-IP0253-Ag-2 Canine NAT2 protein Canine
GM-Tg-bovg-IP0253-Ag-1/ GM-Tg-bovg-IP0253-Ag-2 Bovine NAT2 protein Bovine
GM-Tg-equg-IP0253-Ag-1/ GM-Tg-equg-IP0253-Ag-2 Equine NAT2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0253-Ag-1/ GM-Tg-hg-IP0253-Ag-2; GM-Tg-rg-IP0253-Ag-1/ GM-Tg-rg-IP0253-Ag-2;
GM-Tg-mg-IP0253-Ag-1/ GM-Tg-mg-IP0253-Ag-2; GM-Tg-cynog-IP0253-Ag-1/ GM-Tg-cynog-IP0253-Ag-2;
GM-Tg-felg-IP0253-Ag-1/ GM-Tg-felg-IP0253-Ag-2; GM-Tg-cang-IP0253-Ag-1/ GM-Tg-cang-IP0253-Ag-2;
GM-Tg-bovg-IP0253-Ag-1/ GM-Tg-bovg-IP0253-Ag-2; GM-Tg-equg-IP0253-Ag-1/ GM-Tg-equg-IP0253-Ag-2
Products Name NAT2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NAT2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NAT2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.