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Target
sublocation: Introcelluar Protein.
This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second polymorphic arylamine N-acetyltransferase gene (NAT1), is located near this gene (NAT2). [provided by RefSeq, Sep 2019]
| Target ID |
GM-IP0253
|
| Target Name |
NAT2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10
|
| Gene ID |
10 (Homo sapiens)
|
| Target Alternative Names |
NAT2,AAC2,PNAT,NAT-2
|
| Uniprot Accession |
P11245
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, Chemical carcinogenesis - DNA adducts
|
| Gene Ensembl |
ENSG00000156006
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of NAT2 cDNA Clones/ORF Plasmid
NAT2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10 | Pre-made Human NAT2/AAC2/PNAT siRNA oligo Duplex | 10 | Human | In-vitro grade; in-vivo grade | Detail |
NAT2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0253-Ab | Human | Anti-Human NAT2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
NAT2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0253-Ag | Human | Human NAT2 recombinant protein | Mammalian cell | Detail |
