Recombinant multi-species SPTLC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SPTLC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. [provided by RefSeq, Jul 2013]
The Alternative Names of target: ALS27,E030036H05,HSAN1,HSN1,LBC1,LCB 1,LCB1,Lcb1,Long chain base biosynthesis protein 1 (LCB 1),RGD1306617,SPT 1,SPT1,SPT1),SPTI,SPTLC1,Serine palmitoyltransferase 1,Serine-palmitoyl-CoA transferase 1 (SPT 1,Spt1,Sptlc1

Target products collectionGo to SPTLC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0242-Ag-1/ GM-Tg-hg-IP0242-Ag-2 Human SPTLC1 protein Human
GM-Tg-rg-IP0242-Ag-1/ GM-Tg-rg-IP0242-Ag-2 Rat SPTLC1 protein Rat
GM-Tg-mg-IP0242-Ag-1/ GM-Tg-mg-IP0242-Ag-2 Mouse SPTLC1 protein Mouse
GM-Tg-cynog-IP0242-Ag-1/ GM-Tg-cynog-IP0242-Ag-2 Cynomolgus/Rhesus macaque SPTLC1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0242-Ag-1/ GM-Tg-felg-IP0242-Ag-2 Feline SPTLC1 protein Feline
GM-Tg-cang-IP0242-Ag-1/ GM-Tg-cang-IP0242-Ag-2 Canine SPTLC1 protein Canine
GM-Tg-bovg-IP0242-Ag-1/ GM-Tg-bovg-IP0242-Ag-2 Bovine SPTLC1 protein Bovine
GM-Tg-equg-IP0242-Ag-1/ GM-Tg-equg-IP0242-Ag-2 Equine SPTLC1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0242-Ag-1/ GM-Tg-hg-IP0242-Ag-2; GM-Tg-rg-IP0242-Ag-1/ GM-Tg-rg-IP0242-Ag-2;
GM-Tg-mg-IP0242-Ag-1/ GM-Tg-mg-IP0242-Ag-2; GM-Tg-cynog-IP0242-Ag-1/ GM-Tg-cynog-IP0242-Ag-2;
GM-Tg-felg-IP0242-Ag-1/ GM-Tg-felg-IP0242-Ag-2; GM-Tg-cang-IP0242-Ag-1/ GM-Tg-cang-IP0242-Ag-2;
GM-Tg-bovg-IP0242-Ag-1/ GM-Tg-bovg-IP0242-Ag-2; GM-Tg-equg-IP0242-Ag-1/ GM-Tg-equg-IP0242-Ag-2
Products Name SPTLC1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SPTLC1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SPTLC1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.